OMP ST:71182 ! Escherichia coli K-12 GSO190

Strain Summary

Strain Name	Escherichia coli K-12 GSO190
Synonyms
Taxon Information	Pangenome: Escherichia coli Subspecies and/or strain: K-12 NCBI Taxonomy ID: 83333
Genotype	F- Lambda- rph-1 ssrA(del)::FRT-kan-FRT
Strain Reference	PMID:19734312
Strain availability
Ancestry	parent:OMP ST:159 ! Escherichia coli K-12 MG1655
Annotated phenotypes
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Phenotype Annotation

Annotation ID	Qualifier	OMP ID	OMP term name	Relative phenotype information	Experimental condition	ECO ID	ECO term name	Reference	Annotation Extension	Notes
OMP_AN:37051		OMP:0006057	decreased resistance to aminoglycoside	Relative to: OMP_AN:27525 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Amikacin sulfate salt (disulfate)	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:2638) Amikacin sulfate salt (disulfate)	chemical concentration= 0.2 ug/ml normalized fitness= -4.73
OMP_AN:37052		OMP:0006036	decreased resistance to macrolide	Relative to: OMP_AN:27518 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Azithromycin	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:2955) Azithromycin	chemical concentration= 1 ug/ml normalized fitness= -5.07
OMP_AN:37053		OMP:0007249	decreased resistance to a chemical	Relative to: OMP_AN:27514 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Chlorpromazine hydrochloride	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:3649) Chlorpromazine hydrochloride	chemical concentration= 6 uM normalized fitness= -7.26
OMP_AN:37054		OMP:0006036	decreased resistance to macrolide	Relative to: OMP_AN:27520 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Erythromycin	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:42355) Erythromycin	chemical concentration= 5 ug/ml normalized fitness= -7.51
OMP_AN:37055		OMP:0007879	decreased resistance to an antimicrobial agent	Relative to: OMP_AN:27515 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Fusidic acid sodium salt	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CID:126963539) Fusidic acid sodium salt	chemical concentration= 50 ug/ml normalized fitness= -3.79
OMP_AN:37056		OMP:0007249	decreased resistance to a chemical	Relative to: OMP_AN:27510 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Mitomycin C	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:27504) Mitomycin C	chemical concentration= 0.1 ug/ml normalized fitness= -5.37
OMP_AN:37057		OMP:0007250	increased resistance to a chemical	Relative to: OMP_AN:27593 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:(-)-Norepinephrine	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:18357) (-)-Norepinephrine	chemical concentration= 100 uM normalized fitness= 4.27
OMP_AN:37058		OMP:0007249	decreased resistance to a chemical	Relative to: OMP_AN:27567 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Theophylline anhydrous	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:28177) Theophylline anhydrous	chemical concentration= 100 ug/ml normalized fitness= -5.01
OMP_AN:37059		OMP:0007250	increased resistance to a chemical	Relative to: OMP_AN:27568 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:(±)-Verapamil hydrochloride	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:53188) (±)-Verapamil hydrochloride	chemical concentration= 0.1 mM normalized fitness= 4.35
OMP_AN:37060		OMP:0006057	decreased resistance to aminoglycoside	Relative to: OMP_AN:27526 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Gentamicin sulfate salt	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:5312) Gentamicin sulfate salt	chemical concentration= 0.05 ug/ml normalized fitness= -5.2
OMP_AN:37061		OMP:0007879	decreased resistance to an antimicrobial agent	Relative to: OMP_AN:27504 Genotype differences: +ssrA(del) -DE(araD-araB)567 -DE(rhaD-rhaB)568 -hsdR514 -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Novobiocin sodium salt	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:31924) Novobiocin sodium salt	chemical concentration= 8 ug/ml normalized fitness= -6.3
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References

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