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OMP ST:1026 ! Escherichia coli K-12 JW3595

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Rows in conflict with the working copy:

Annotation ID Qualifier OMP ID OMP term name Relative phenotype information Experimental condition ECO ID ECO term name Reference Annotation Extension Notes

public

OMP_AN:33776

OMP:0006036

decreased resistance to macrolide

Relative to: OMP_AN:27518


Genotype differences:

+rfaF732(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Azithromycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:2955) Azithromycin

  • chemical concentration= 1 ug/ml
  • normalized fitness= -7.97

public

OMP_AN:33777

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27571


Genotype differences:

+rfaF732(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:CCCP (Carbonyl cyanide 3-chlorophenylhydrazone)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:3259) CCCP (Carbonyl cyanide 3-chlorophenylhydrazone)

  • chemical concentration= 2 ug/ml
  • normalized fitness= -3.69

public

OMP_AN:33778

OMP:0006044

decreased resistance to beta-lactam

Relative to: OMP_AN:27535


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Cefsulodin sodium salt hydrate

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:31380) Cefsulodin sodium salt hydrate

  • chemical concentration= 24 ug/ml
  • normalized fitness= -5.29

public

OMP_AN:33779

OMP:0007250

increased resistance to a chemical

Relative to: OMP_AN:27511


Genotype differences:

+rfaF732(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:(-)-Epinephrine

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:28918) (-)-Epinephrine

  • chemical concentration= 250 uM
  • normalized fitness= 3.82

public

OMP_AN:33780

OMP:0006036

decreased resistance to macrolide

Relative to: OMP_AN:27520


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Erythromycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:42355) Erythromycin

  • chemical concentration= 10 ug/ml
  • normalized fitness= -3.61

public

OMP_AN:33781

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27515


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Fusidic acid sodium salt

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:126963539) Fusidic acid sodium salt

  • chemical concentration= 50 ug/ml
  • normalized fitness= -7.03

public

OMP_AN:33782

OMP:0006044

decreased resistance to beta-lactam

Relative to: OMP_AN:27537


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Mecillinam

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:51208) Mecillinam

  • chemical concentration= 0.03 ug/ml
  • normalized fitness= -3.46

public

OMP_AN:33783

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27513


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Phenazine methosulfate (PMS)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8055) Phenazine methosulfate (PMS)

  • chemical concentration= 0.1 mM
  • normalized fitness= -4.25

public

OMP_AN:33784

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27573


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Procaine hydrochloride

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8431) Procaine hydrochloride

  • chemical concentration= 10 mM
  • normalized fitness= -4.15

public

OMP_AN:33785

OMP:0007878

increased resistance to an antimicrobial agent

Relative to: OMP_AN:27553


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Puromycin dihydrochloride

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8642) Puromycin dihydrochloride

  • chemical concentration= 5 ug/ml
  • normalized fitness= 5.52

public

OMP_AN:33786

OMP:0006040

decreased resistance to quinolone

Relative to: OMP_AN:27543


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Streptonigrin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:9287) Streptonigrin

  • chemical concentration= 0.5 ug/ml
  • normalized fitness= -4.83

public

OMP_AN:33787

OMP:0006058

increased resistance to aminoglycoside

Relative to: OMP_AN:27529


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Tobramycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:28864) Tobramycin

  • chemical concentration= 0.05 ug/ml
  • normalized fitness= 4.04

public

OMP_AN:33788

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27588


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Triclosan/Irgasan

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:164200) Triclosan/Irgasan

  • chemical concentration= 0.05 ug/ml
  • normalized fitness= -15.74

public

OMP_AN:33789

OMP:0007250

increased resistance to a chemical

Relative to: OMP_AN:27568


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:(±)-Verapamil hydrochloride

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:53188) (±)-Verapamil hydrochloride

  • chemical concentration= 0.1 mM
  • normalized fitness= 4.11

public

OMP_AN:33790

OMP:0006041

increased resistance to quinolone

Relative to: OMP_AN:27539


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Ciprofloxacin hydrochloride hydrate

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:59936) Ciprofloxacin hydrochloride hydrate

  • chemical concentration= 0.008 ug/ml
  • normalized fitness= 3.69

public

OMP_AN:33791

OMP:0006040

decreased resistance to quinolone

Relative to: OMP_AN:27541


Genotype differences:

+rfaF732(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Nalidixic acid sodium salt

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:3864541) Nalidixic acid sodium salt

  • chemical concentration= 2 ug/ml
  • normalized fitness= -4.7

public

OMP_AN:33792

OMP:0007010

decreased population growth at alkaline pH

Relative to: OMP_AN:27623


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

pH:8.0?

  • temperature:37C
  • medium:LB agar
  • medium:TAPS
  • pH:8.0

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

  • chemical concentration= pH 8
  • normalized fitness= -7.32

public

OMP_AN:33793

OMP:0007008

decreased population growth at acidic pH

Relative to: OMP_AN:27622


Genotype differences:

+rfaF732(del)


Condition differences:

pH:4.0?

  • temperature:37C
  • medium:LB agar
  • medium:MES-HOMOPIPES
  • pH:4.0

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

  • chemical concentration= pH 4
  • normalized fitness= -3.43

public

OMP_AN:33794

OMP:0007009

increased population growth at acidic pH

Relative to: OMP_AN:27622


Genotype differences:

+rfaF732(del)


Condition differences:

pH:6.0?

  • temperature:37C
  • medium:LB agar
  • medium:MES-HOMOPIPES
  • pH:6.0

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

  • chemical concentration= 6
  • normalized fitness= 6.5

public

OMP_AN:33795

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27591


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:45924 + CHEBI:9331) Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331)

  • chemical concentration= 0.1 + 50 ug/ml
  • normalized fitness= -5.04

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Annotation ID Qualifier OMP ID OMP term name Relative phenotype information Experimental condition ECO ID ECO term name Reference Annotation Extension Notes

public

OMP_AN:937

OMP:0007092

decreased cell motility by swarming

Relative to: OMP_AN:881


Genotype differences:

+DE(araD-araB)567 +DE(rhaD-rhaB)568 +hsdR514 +lacZ4787(del)( +rfaF732(del) -IN(rrnD-rrnE)1


Condition differences:

no differences

  • temperature:33C
  • medium:swarming motility medium

ECO:0005803

motility assay evidence

PMID:17122336

public

OMP_AN:1141

OMP:0005324

altered cell motility by swimming

Relative to: OMP_AN:882


Genotype differences:

+DE(araD-araB)567 +DE(rhaD-rhaB)568 +hsdR514 +lacZ4787(del)( +rfaF732(del) -IN(rrnD-rrnE)1


Condition differences:

no differences

  • temperature:33C
  • medium:swimming motility medium

ECO:0005803

motility assay evidence

PMID:17122336

public

OMP_AN:33776

OMP:0006036

decreased resistance to macrolide

Relative to: OMP_AN:27518


Genotype differences:

+rfaF732(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Azithromycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:2955) Azithromycin

  • chemical concentration= 1 ug/ml
  • normalized fitness= -7.97

public

OMP_AN:33777

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27571


Genotype differences:

+rfaF732(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:CCCP (Carbonyl cyanide 3-chlorophenylhydrazone)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:3259) CCCP (Carbonyl cyanide 3-chlorophenylhydrazone)

  • chemical concentration= 2 ug/ml
  • normalized fitness= -3.69

public

OMP_AN:33778

OMP:0006044

decreased resistance to beta-lactam

Relative to: OMP_AN:27535


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Cefsulodin sodium salt hydrate

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:31380) Cefsulodin sodium salt hydrate

  • chemical concentration= 24 ug/ml
  • normalized fitness= -5.29

public

OMP_AN:33779

OMP:0007250

increased resistance to a chemical

Relative to: OMP_AN:27511


Genotype differences:

+rfaF732(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:(-)-Epinephrine

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:28918) (-)-Epinephrine

  • chemical concentration= 250 uM
  • normalized fitness= 3.82

public

OMP_AN:33780

OMP:0006036

decreased resistance to macrolide

Relative to: OMP_AN:27520


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Erythromycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:42355) Erythromycin

  • chemical concentration= 10 ug/ml
  • normalized fitness= -3.61

public

OMP_AN:33781

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27515


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Fusidic acid sodium salt

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:126963539) Fusidic acid sodium salt

  • chemical concentration= 50 ug/ml
  • normalized fitness= -7.03

public

OMP_AN:33782

OMP:0006044

decreased resistance to beta-lactam

Relative to: OMP_AN:27537


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Mecillinam

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:51208) Mecillinam

  • chemical concentration= 0.03 ug/ml
  • normalized fitness= -3.46

public

OMP_AN:33783

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27513


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Phenazine methosulfate (PMS)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8055) Phenazine methosulfate (PMS)

  • chemical concentration= 0.1 mM
  • normalized fitness= -4.25

public

OMP_AN:33784

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27573


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Procaine hydrochloride

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8431) Procaine hydrochloride

  • chemical concentration= 10 mM
  • normalized fitness= -4.15

public

OMP_AN:33785

OMP:0007878

increased resistance to an antimicrobial agent

Relative to: OMP_AN:27553


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Puromycin dihydrochloride

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8642) Puromycin dihydrochloride

  • chemical concentration= 5 ug/ml
  • normalized fitness= 5.52

public

OMP_AN:33786

OMP:0006040

decreased resistance to quinolone

Relative to: OMP_AN:27543


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Streptonigrin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:9287) Streptonigrin

  • chemical concentration= 0.5 ug/ml
  • normalized fitness= -4.83

public

OMP_AN:33787

OMP:0006058

increased resistance to aminoglycoside

Relative to: OMP_AN:27529


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Tobramycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:28864) Tobramycin

  • chemical concentration= 0.05 ug/ml
  • normalized fitness= 4.04

public

OMP_AN:33788

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27588


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Triclosan/Irgasan

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:164200) Triclosan/Irgasan

  • chemical concentration= 0.05 ug/ml
  • normalized fitness= -15.74

public

OMP_AN:33789

OMP:0007250

increased resistance to a chemical

Relative to: OMP_AN:27568


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:(±)-Verapamil hydrochloride

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:53188) (±)-Verapamil hydrochloride

  • chemical concentration= 0.1 mM
  • normalized fitness= 4.11

public

OMP_AN:33790

OMP:0006041

increased resistance to quinolone

Relative to: OMP_AN:27539


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Ciprofloxacin hydrochloride hydrate

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:59936) Ciprofloxacin hydrochloride hydrate

  • chemical concentration= 0.008 ug/ml
  • normalized fitness= 3.69

public

OMP_AN:33791

OMP:0006040

decreased resistance to quinolone

Relative to: OMP_AN:27541


Genotype differences:

+rfaF732(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Nalidixic acid sodium salt

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:3864541) Nalidixic acid sodium salt

  • chemical concentration= 2 ug/ml
  • normalized fitness= -4.7

public

OMP_AN:33792

OMP:0007010

decreased population growth at alkaline pH

Relative to: OMP_AN:27623


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

pH:8.0?

  • temperature:37C
  • medium:LB agar
  • medium:TAPS
  • pH:8.0

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

  • chemical concentration= pH 8
  • normalized fitness= -7.32

public

OMP_AN:33793

OMP:0007008

decreased population growth at acidic pH

Relative to: OMP_AN:27622


Genotype differences:

+rfaF732(del)


Condition differences:

pH:4.0?

  • temperature:37C
  • medium:LB agar
  • medium:MES-HOMOPIPES
  • pH:4.0

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

  • chemical concentration= pH 4
  • normalized fitness= -3.43

public

OMP_AN:33794

OMP:0007009

increased population growth at acidic pH

Relative to: OMP_AN:27622


Genotype differences:

+rfaF732(del)


Condition differences:

pH:6.0?

  • temperature:37C
  • medium:LB agar
  • medium:MES-HOMOPIPES
  • pH:6.0

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

  • chemical concentration= 6
  • normalized fitness= 6.5

public

OMP_AN:33795

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27591


Genotype differences:

+lacZ4787(del)( +rfaF732(del) -lacZ4787(del)


Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:45924 + CHEBI:9331) Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331)

  • chemical concentration= 0.1 + 50 ug/ml
  • normalized fitness= -5.04
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