Difference between revisions of "OMP ST:71798 ! Escherichia coli K-12 JW0890"

From OMPwiki
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Line 100: Line 100:
 
*chemical concentration= 0.6%
 
*chemical concentration= 0.6%
 
*normalized fitness= -20.48  
 
*normalized fitness= -20.48  
 +
|-
 +
|
 +
OMP_AN:29395
 +
|
 +
 +
|
 +
OMP:0007070
 +
|
 +
decreased organic carbon source utilization
 +
|
 +
Relative to: OMP_AN:27611
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:Sodium Acetate anhydrous
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:32954) Sodium Acetate anhydrous
 +
|
 +
 +
*chemical concentration= 0.6%
 +
*normalized fitness= -20.48
 +
|-
 +
|
 +
OMP_AN:29396
 +
|
 +
 +
|
 +
OMP:0006044
 +
|
 +
decreased resistance to beta-lactam
 +
|
 +
Relative to: OMP_AN:27530
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:Amoxicillin
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:2676) Amoxicillin
 +
|
 +
 +
*chemical concentration= 0.25 ug/ml
 +
*normalized fitness= -3.68
 +
|-
 +
|
 +
OMP_AN:29397
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27606
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:N-Acetyl-D-glucosamine
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:506227) N-Acetyl-D-glucosamine
 +
|
 +
 +
*chemical concentration= 0.15%
 +
*normalized fitness= -15.64
 +
|-
 +
|
 +
OMP_AN:29398
 +
|
 +
 +
|
 +
OMP:0007070
 +
|
 +
decreased organic carbon source utilization
 +
|
 +
Relative to: OMP_AN:27616
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:N-Acetyl-D-glucosamine
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:506227) N-Acetyl-D-glucosamine
 +
|
 +
 +
*chemical concentration= 0.15%
 +
*normalized fitness= -15.64
 +
|-
 +
|
 +
OMP_AN:29399
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27602
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:D-(+) Glucosamine hydrochloride
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CID:91431) D-(+) Glucosamine hydrochloride
 +
|
 +
 +
*chemical concentration= 0.2%
 +
*normalized fitness= -17.85
 +
|-
 +
|
 +
OMP_AN:29400
 +
|
 +
 +
|
 +
OMP:0007070
 +
|
 +
decreased organic carbon source utilization
 +
|
 +
Relative to: OMP_AN:27612
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:D-(+) Glucosamine hydrochloride
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CID:91431) D-(+) Glucosamine hydrochloride
 +
|
 +
 +
*chemical concentration= 0.2%
 +
*normalized fitness= -17.85
 +
|-
 +
|
 +
OMP_AN:29401
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27603
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:D-Glucose anhydrous
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:42758) D-Glucose anhydrous
 +
|
 +
 +
*chemical concentration= 0.2%
 +
*normalized fitness= -9.64
 +
|-
 +
|
 +
OMP_AN:29402
 +
|
 +
 +
|
 +
OMP:0007070
 +
|
 +
decreased organic carbon source utilization
 +
|
 +
Relative to: OMP_AN:27613
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:D-Glucose anhydrous
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:42758) D-Glucose anhydrous
 +
|
 +
 +
*chemical concentration= 0.2%
 +
*normalized fitness= -9.64
 +
|-
 +
|
 +
OMP_AN:29403
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27604
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:Glycerol
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:17754) Glycerol
 +
|
 +
 +
*chemical concentration= 0.4%
 +
*normalized fitness= -17.31
 +
|-
 +
|
 +
OMP_AN:29404
 +
|
 +
 +
|
 +
OMP:0007070
 +
|
 +
decreased organic carbon source utilization
 +
|
 +
Relative to: OMP_AN:27614
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:Glycerol
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:17754) Glycerol
 +
|
 +
 +
*chemical concentration= 0.4%
 +
*normalized fitness= -17.31
 +
|-
 +
|
 +
OMP_AN:29405
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27605
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:D-(+) Maltose monohydrate
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CID:23615261) D-(+) Maltose monohydrate
 +
|
 +
 +
*chemical concentration= 0.1%
 +
*normalized fitness= -15.45
 +
|-
 +
|
 +
OMP_AN:29406
 +
|
 +
 +
|
 +
OMP:0007070
 +
|
 +
decreased organic carbon source utilization
 +
|
 +
Relative to: OMP_AN:27615
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:D-(+) Maltose monohydrate
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CID:23615261) D-(+) Maltose monohydrate
 +
|
 +
 +
*chemical concentration= 0.1%
 +
*normalized fitness= -15.45
 +
|-
 +
|
 +
OMP_AN:29407
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27600
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:MOPS
 +
*medium:NH4Cl
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:31206) NH4Cl
 +
|
 +
 +
*chemical concentration= 9.5mm
 +
*normalized fitness= -15.39
 +
|-
 +
|
 +
OMP_AN:29408
 +
|
 +
 +
|
 +
OMP:0007032
 +
|
 +
decreased utilization of inorganic nitrogen source
 +
|
 +
Relative to: OMP_AN:27610
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:MOPS
 +
*medium:NH4Cl
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:31206) NH4Cl
 +
|
 +
 +
*chemical concentration= 9.5mm
 +
*normalized fitness= -15.39
 +
|-
 +
|
 +
OMP_AN:29409
 +
|
 +
 +
|
 +
OMP:0007879
 +
|
 +
decreased resistance to an antimicrobial agent
 +
|
 +
Relative to: OMP_AN:27503
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:Nitrofurantoin
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:71415) Nitrofurantoin
 +
|
 +
 +
*chemical concentration=  1.5 ug/ml
 +
*normalized fitness= -3.8
 +
|-
 +
|
 +
OMP_AN:29410
 +
|
 +
 +
|
 +
OMP:0007879
 +
|
 +
decreased resistance to an antimicrobial agent
 +
|
 +
Relative to: OMP_AN:27547
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:Hydrogen peroxide
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:16240) Hydrogen peroxide
 +
|
 +
 +
*chemical concentration= 0.1 mM
 +
*normalized fitness= -3.95
 +
|-
 +
|
 +
OMP_AN:29411
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27607
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:Succinic acid
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:15741) Succinic acid
 +
|
 +
 +
*chemical concentration= 0.3%
 +
*normalized fitness= -12.54
 +
|-
 +
|
 +
OMP_AN:29412
 +
|
 +
 +
|
 +
OMP:0007070
 +
|
 +
decreased organic carbon source utilization
 +
|
 +
Relative to: OMP_AN:27617
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:M9
 +
*medium:Succinic acid
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:15741) Succinic acid
 +
|
 +
 +
*chemical concentration= 0.3%
 +
*normalized fitness= -12.54
 +
|-
 +
|
 +
OMP_AN:29413
 +
|
 +
 +
|
 +
OMP:0007903
 +
|
 +
decreased resistance to bile acids
 +
|
 +
Relative to: OMP_AN:27584
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:Taurocholic acid sodium salt hydrate
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CID:23687511) Taurocholic acid sodium salt hydrate
 +
|
 +
 +
*chemical concentration=  1 %
 +
*normalized fitness= -3.35
 +
|-
 +
|
 +
OMP_AN:29414
 +
|
 +
 +
|
 +
OMP:0006057
 +
|
 +
decreased resistance to aminoglycoside
 +
|
 +
Relative to: OMP_AN:27529
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:Tobramycin
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:28864) Tobramycin
 +
|
 +
 +
*chemical concentration= 0.05 ug/ml
 +
*normalized fitness= -4.83
 +
|-
 +
|
 +
OMP_AN:29415
 +
|
 +
 +
|
 +
OMP:0007249
 +
|
 +
decreased resistance to a chemical
 +
|
 +
Relative to: OMP_AN:27568
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:(±)-Verapamil hydrochloride
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:53188) (±)-Verapamil hydrochloride
 +
|
 +
 +
*chemical concentration= 0.1 mM
 +
*normalized fitness= -3.76
 +
|-
 +
|
 +
OMP_AN:29416
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27598
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:MOPS
 +
*medium:Iron excess-FeSO4 heptahydride
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:75836) Iron excess-FeSO4 heptahydride
 +
|
 +
 +
*chemical concentration= 1mM (MOPS; normal 100uM)
 +
*normalized fitness= -13.52
 +
|-
 +
|
 +
OMP_AN:29417
 +
|
 +
 +
|
 +
OMP:0007886
 +
|
 +
decreased resistance to a metal
 +
|
 +
Relative to: OMP_AN:27608
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:MOPS
 +
*medium:Iron excess-FeSO4 heptahydride
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:75836) Iron excess-FeSO4 heptahydride
 +
|
 +
 +
*chemical concentration= 1mM (MOPS; normal 100uM)
 +
*normalized fitness= -13.52
 +
|-
 +
|
 +
OMP_AN:29418
 +
|
 +
 +
|
 +
OMP:0007075
 +
|
 +
decreased growth factor requirement
 +
|
 +
Relative to: OMP_AN:27599
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:MOPS
 +
*medium:Iron starvation-FeSO4·7H2O
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:75836) Iron starvation-FeSO4·7H2O
 +
|
 +
 +
*chemical concentration= 2uM (MOPS; normal 100uM)
 +
*normalized fitness= -10.94
 +
|-
 +
|
 +
OMP_AN:29419
 +
|
 +
 +
|
 +
OMP:0007937
 +
|
 +
decreased resistance to nutrient limitation
 +
|
 +
Relative to: OMP_AN:27609
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:MOPS
 +
*medium:Iron starvation-FeSO4·7H2O
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:75836) Iron starvation-FeSO4·7H2O
 +
|
 +
 +
*chemical concentration= 2uM (MOPS; normal 100uM)
 +
*normalized fitness= -10.94
 +
|-
 +
|
 +
OMP_AN:29420
 +
|
 +
 +
|
 +
OMP:0007008
 +
|
 +
decreased population growth at acidic pH
 +
|
 +
Relative to: OMP_AN:27622
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:MES-HOMOPIPES
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (**SID:329817955 SID:57651422) MES-HOMOPIPES
 +
|
 +
 +
*chemical concentration=  6
 +
*normalized fitness= -3.46
 +
|-
 +
|
 +
OMP_AN:29421
 +
|
 +
 +
|
 +
OMP:0007879
 +
|
 +
decreased resistance to an antimicrobial agent
 +
|
 +
Relative to: OMP_AN:27565
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:Polymyxin B sulfate
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:8310) Polymyxin B sulfate
 +
|
 +
 +
*chemical concentration=  4 ug/ml
 +
*normalized fitness= -4.88
 +
|-
 +
|
 +
OMP_AN:29422
 +
|
 +
 +
|
 +
OMP:0006057
 +
|
 +
decreased resistance to aminoglycoside
 +
|
 +
Relative to: OMP_AN:27527
 +
 +
<hr>Genotype differences:<br>
 +
+lacZ4787(del)( +serC731(del)  -lacZ4787(del)
 +
<hr>Condition differences:<br>
 +
no differences
 +
|
 +
 +
*temperature:37C
 +
*medium:LB agar
 +
*medium:Spectinomycin dihydrochloride pentahydrate
 +
|
 +
ECO:0007005
 +
|
 +
high throughput direct assay evidence used in manual assertion
 +
|
 +
PMID:21185072
 +
|
 +
towards some (CHEBI:9217) Spectinomycin dihydrochloride pentahydrate
 +
|
 +
 +
*chemical concentration=  6 ug/ml
 +
*normalized fitness= -5.67
  
 
|- class="tableEdit_footer"  
 
|- class="tableEdit_footer"  

Latest revision as of 21:17, 22 October 2019

Strain Summary

Strain Name

Escherichia coli K-12 JW0890

Synonyms

JW0890-1

Taxon Information
  • Pangenome: Escherichia coli
  • Subspecies and/or strain: K-12
  • NCBI Taxonomy ID: 83333
Genotype

DE(araD-araB)567 DE(rhaD-rhaB)568 F- Lambda- hsdR514 lacZ4787(del)(::rrnB-3) rph-1 serC731(del)::FRT-kan-FRT

Strain Reference
Strain availability

Coli Genetic Stock Center

Ancestry

parent:OMP ST:800 ! Escherichia coli K-12 BW25113

Annotated phenotypes


edit table


Notes

Phenotype Annotation

Annotation ID Qualifier OMP ID OMP term name Relative phenotype information Experimental condition ECO ID ECO term name Reference Annotation Extension Notes

OMP_AN:29394

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27601

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:Sodium Acetate anhydrous
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:32954) Sodium Acetate anhydrous

  • chemical concentration= 0.6%
  • normalized fitness= -20.48

OMP_AN:29395

OMP:0007070

decreased organic carbon source utilization

Relative to: OMP_AN:27611

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:Sodium Acetate anhydrous
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:32954) Sodium Acetate anhydrous

  • chemical concentration= 0.6%
  • normalized fitness= -20.48

OMP_AN:29396

OMP:0006044

decreased resistance to beta-lactam

Relative to: OMP_AN:27530

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Amoxicillin
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:2676) Amoxicillin

  • chemical concentration= 0.25 ug/ml
  • normalized fitness= -3.68

OMP_AN:29397

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27606

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:N-Acetyl-D-glucosamine
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:506227) N-Acetyl-D-glucosamine

  • chemical concentration= 0.15%
  • normalized fitness= -15.64

OMP_AN:29398

OMP:0007070

decreased organic carbon source utilization

Relative to: OMP_AN:27616

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:N-Acetyl-D-glucosamine
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:506227) N-Acetyl-D-glucosamine

  • chemical concentration= 0.15%
  • normalized fitness= -15.64

OMP_AN:29399

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27602

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:D-(+) Glucosamine hydrochloride
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CID:91431) D-(+) Glucosamine hydrochloride

  • chemical concentration= 0.2%
  • normalized fitness= -17.85

OMP_AN:29400

OMP:0007070

decreased organic carbon source utilization

Relative to: OMP_AN:27612

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:D-(+) Glucosamine hydrochloride
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CID:91431) D-(+) Glucosamine hydrochloride

  • chemical concentration= 0.2%
  • normalized fitness= -17.85

OMP_AN:29401

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27603

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:D-Glucose anhydrous
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:42758) D-Glucose anhydrous

  • chemical concentration= 0.2%
  • normalized fitness= -9.64

OMP_AN:29402

OMP:0007070

decreased organic carbon source utilization

Relative to: OMP_AN:27613

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:D-Glucose anhydrous
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:42758) D-Glucose anhydrous

  • chemical concentration= 0.2%
  • normalized fitness= -9.64

OMP_AN:29403

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27604

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:Glycerol
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:17754) Glycerol

  • chemical concentration= 0.4%
  • normalized fitness= -17.31

OMP_AN:29404

OMP:0007070

decreased organic carbon source utilization

Relative to: OMP_AN:27614

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:Glycerol
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:17754) Glycerol

  • chemical concentration= 0.4%
  • normalized fitness= -17.31

OMP_AN:29405

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27605

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:D-(+) Maltose monohydrate
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CID:23615261) D-(+) Maltose monohydrate

  • chemical concentration= 0.1%
  • normalized fitness= -15.45

OMP_AN:29406

OMP:0007070

decreased organic carbon source utilization

Relative to: OMP_AN:27615

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:D-(+) Maltose monohydrate
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CID:23615261) D-(+) Maltose monohydrate

  • chemical concentration= 0.1%
  • normalized fitness= -15.45

OMP_AN:29407

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27600

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:MOPS
  • medium:NH4Cl
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:31206) NH4Cl

  • chemical concentration= 9.5mm
  • normalized fitness= -15.39

OMP_AN:29408

OMP:0007032

decreased utilization of inorganic nitrogen source

Relative to: OMP_AN:27610

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:MOPS
  • medium:NH4Cl
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:31206) NH4Cl

  • chemical concentration= 9.5mm
  • normalized fitness= -15.39

OMP_AN:29409

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27503

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Nitrofurantoin
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:71415) Nitrofurantoin

  • chemical concentration= 1.5 ug/ml
  • normalized fitness= -3.8

OMP_AN:29410

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27547

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Hydrogen peroxide
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:16240) Hydrogen peroxide

  • chemical concentration= 0.1 mM
  • normalized fitness= -3.95

OMP_AN:29411

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27607

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:Succinic acid
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:15741) Succinic acid

  • chemical concentration= 0.3%
  • normalized fitness= -12.54

OMP_AN:29412

OMP:0007070

decreased organic carbon source utilization

Relative to: OMP_AN:27617

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:M9
  • medium:Succinic acid
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:15741) Succinic acid

  • chemical concentration= 0.3%
  • normalized fitness= -12.54

OMP_AN:29413

OMP:0007903

decreased resistance to bile acids

Relative to: OMP_AN:27584

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Taurocholic acid sodium salt hydrate
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CID:23687511) Taurocholic acid sodium salt hydrate

  • chemical concentration= 1 %
  • normalized fitness= -3.35

OMP_AN:29414

OMP:0006057

decreased resistance to aminoglycoside

Relative to: OMP_AN:27529

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Tobramycin
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:28864) Tobramycin

  • chemical concentration= 0.05 ug/ml
  • normalized fitness= -4.83

OMP_AN:29415

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27568

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:(±)-Verapamil hydrochloride
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:53188) (±)-Verapamil hydrochloride

  • chemical concentration= 0.1 mM
  • normalized fitness= -3.76

OMP_AN:29416

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27598

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:MOPS
  • medium:Iron excess-FeSO4 heptahydride
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:75836) Iron excess-FeSO4 heptahydride

  • chemical concentration= 1mM (MOPS; normal 100uM)
  • normalized fitness= -13.52

OMP_AN:29417

OMP:0007886

decreased resistance to a metal

Relative to: OMP_AN:27608

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:MOPS
  • medium:Iron excess-FeSO4 heptahydride
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:75836) Iron excess-FeSO4 heptahydride

  • chemical concentration= 1mM (MOPS; normal 100uM)
  • normalized fitness= -13.52

OMP_AN:29418

OMP:0007075

decreased growth factor requirement

Relative to: OMP_AN:27599

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:MOPS
  • medium:Iron starvation-FeSO4·7H2O
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:75836) Iron starvation-FeSO4·7H2O

  • chemical concentration= 2uM (MOPS; normal 100uM)
  • normalized fitness= -10.94

OMP_AN:29419

OMP:0007937

decreased resistance to nutrient limitation

Relative to: OMP_AN:27609

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:MOPS
  • medium:Iron starvation-FeSO4·7H2O
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:75836) Iron starvation-FeSO4·7H2O

  • chemical concentration= 2uM (MOPS; normal 100uM)
  • normalized fitness= -10.94

OMP_AN:29420

OMP:0007008

decreased population growth at acidic pH

Relative to: OMP_AN:27622

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:MES-HOMOPIPES
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (**SID:329817955 SID:57651422) MES-HOMOPIPES

  • chemical concentration= 6
  • normalized fitness= -3.46

OMP_AN:29421

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27565

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Polymyxin B sulfate
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:8310) Polymyxin B sulfate

  • chemical concentration= 4 ug/ml
  • normalized fitness= -4.88

OMP_AN:29422

OMP:0006057

decreased resistance to aminoglycoside

Relative to: OMP_AN:27527

Genotype differences:

+lacZ4787(del)( +serC731(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Spectinomycin dihydrochloride pentahydrate
 ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[2]

towards some (CHEBI:9217) Spectinomycin dihydrochloride pentahydrate

  • chemical concentration= 6 ug/ml
  • normalized fitness= -5.67
edit table


Additional Information

Links

References

See Help:References for how to manage references in OMPwiki.

  1. ↑ Baba, T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2 2006.0008 PubMed OMPwiki page
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 2.20 2.21 2.22 2.23 2.24 2.25 2.26 2.27 2.28 Nichols, RJ et al. (2011) Phenotypic landscape of a bacterial cell. Cell 144 143-56 PubMed OMPwiki page
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