Difference between revisions of "OMP ST:71245 ! Escherichia coli K-12 JW0052"
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* | * | ||
*normalized fitness= -4.8 | *normalized fitness= -4.8 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27865 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0006036 | ||
+ | | | ||
+ | decreased resistance to macrolide | ||
+ | | | ||
+ | Relative to: OMP_AN:27518 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Azithromycin | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:2955) Azithromycin | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 1 ug/ml | ||
+ | *normalized fitness= -6.5 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27866 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007173 | ||
+ | | | ||
+ | decreased resistance to host defense peptides | ||
+ | | | ||
+ | Relative to: OMP_AN:27562 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Cecropin B | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CID:16130488) Cecropin B | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 0.1 ug/ml | ||
+ | *normalized fitness= -4.88 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27867 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0006037 | ||
+ | | | ||
+ | increased resistance to macrolide | ||
+ | | | ||
+ | Relative to: OMP_AN:27519 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Clarithromycin | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:3732) Clarithromycin | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 0.1 ug/ml | ||
+ | *normalized fitness= 3.92 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27868 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007249 | ||
+ | | | ||
+ | decreased resistance to a chemical | ||
+ | | | ||
+ | Relative to: OMP_AN:27510 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Mitomycin C | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:27504) Mitomycin C | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 0.1 ug/ml | ||
+ | *normalized fitness= -8.77 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27869 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007879 | ||
+ | | | ||
+ | decreased resistance to an antimicrobial agent | ||
+ | | | ||
+ | Relative to: OMP_AN:27553 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Puromycin dihydrochloride | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:8642) Puromycin dihydrochloride | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 5 ug/ml | ||
+ | *normalized fitness= -4.5 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27870 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007896 | ||
+ | | | ||
+ | decreased resistance to a surfactant | ||
+ | | | ||
+ | Relative to: OMP_AN:27582 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:SDS | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:8984) SDS | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 0.5 % | ||
+ | *normalized fitness= -11.66 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27871 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007903 | ||
+ | | | ||
+ | decreased resistance to bile acids | ||
+ | | | ||
+ | Relative to: OMP_AN:27584 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Taurocholic acid sodium salt hydrate | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CID:23687511) Taurocholic acid sodium salt hydrate | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 0.5 % | ||
+ | *normalized fitness= -4.6 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27872 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007249 | ||
+ | | | ||
+ | decreased resistance to a chemical | ||
+ | | | ||
+ | Relative to: OMP_AN:27567 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Theophylline anhydrous | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:28177) Theophylline anhydrous | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 100 ug/ml | ||
+ | *normalized fitness= -5.65 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27873 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007879 | ||
+ | | | ||
+ | decreased resistance to an antimicrobial agent | ||
+ | | | ||
+ | Relative to: OMP_AN:27588 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Triclosan/Irgasan | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:164200) Triclosan/Irgasan | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 0.05 ug/ml | ||
+ | *normalized fitness= -3.71 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27874 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007879 | ||
+ | | | ||
+ | decreased resistance to an antimicrobial agent | ||
+ | | | ||
+ | Relative to: OMP_AN:27560 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Bacitracin Zinc Sulfate | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CID:16219032) Bacitracin Zinc Sulfate | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 300 ug/ml | ||
+ | *normalized fitness= -8.89 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27875 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007879 | ||
+ | | | ||
+ | decreased resistance to an antimicrobial agent | ||
+ | | | ||
+ | Relative to: OMP_AN:27504 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Novobiocin sodium salt | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:31924) Novobiocin sodium salt | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 8 ug/ml | ||
+ | *normalized fitness= -4.58 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27876 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007008 | ||
+ | | | ||
+ | decreased population growth at acidic pH | ||
+ | | | ||
+ | Relative to: OMP_AN:27622 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:MES-HOMOPIPES | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (**SID:329817955 SID:57651422) MES-HOMOPIPES | ||
+ | | | ||
+ | |||
+ | *chemical concentration= pH 4 | ||
+ | *normalized fitness= -14.8 | ||
+ | |- | ||
+ | | | ||
+ | OMP_AN:27877 | ||
+ | | | ||
+ | |||
+ | | | ||
+ | OMP:0007879 | ||
+ | | | ||
+ | decreased resistance to an antimicrobial agent | ||
+ | | | ||
+ | Relative to: OMP_AN:27591 | ||
+ | |||
+ | <hr>Genotype differences:<br> | ||
+ | +lacZ4787(del)( +surA765(del) -lacZ4787(del) | ||
+ | <hr>Condition differences:<br> | ||
+ | no differences | ||
+ | | | ||
+ | |||
+ | *temperature:37C | ||
+ | *medium:LB agar | ||
+ | *medium:Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331) | ||
+ | | | ||
+ | ECO:0007005 | ||
+ | | | ||
+ | high throughput direct assay evidence used in manual assertion | ||
+ | | | ||
+ | PMID:21185072 | ||
+ | | | ||
+ | towards some (CHEBI:45924 + CHEBI:9331) Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331) | ||
+ | | | ||
+ | |||
+ | *chemical concentration= 0.1 + 50 ug/ml | ||
+ | *normalized fitness= -4.36 | ||
|- class="tableEdit_footer" | |- class="tableEdit_footer" |
Latest revision as of 20:32, 22 October 2019
Contents
Strain Summary
Strain Name |
Escherichia coli K-12 JW0052 |
---|---|
Synonyms |
JW0052-1 |
Taxon Information |
|
Genotype |
DE(araD-araB)567 DE(rhaD-rhaB)568 F- Lambda- hsdR514 lacZ4787(del)(::rrnB-3) rph-1 surA765(del)::FRT-kan-FRT |
Strain Reference | |
Strain availability | |
Ancestry | |
Annotated phenotypes |
|
Notes
Phenotype Annotation
Annotation ID | Qualifier | OMP ID | OMP term name | Relative phenotype information | Experimental condition | ECO ID | ECO term name | Reference | Annotation Extension | Notes |
---|---|---|---|---|---|---|---|---|---|---|
OMP_AN:27863 |
OMP:0007249 |
decreased resistance to a chemical |
Relative to: OMP_AN:27575 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:74728) Acriflavine (acriflavinium chloride) |
| ||
OMP_AN:27864 |
OMP:0007927 |
decreased anaerobic population growth |
Relative to: OMP_AN:27618 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
| |||
OMP_AN:27865 |
OMP:0006036 |
decreased resistance to macrolide |
Relative to: OMP_AN:27518 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:2955) Azithromycin |
| ||
OMP_AN:27866 |
OMP:0007173 |
decreased resistance to host defense peptides |
Relative to: OMP_AN:27562 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CID:16130488) Cecropin B |
| ||
OMP_AN:27867 |
OMP:0006037 |
increased resistance to macrolide |
Relative to: OMP_AN:27519 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:3732) Clarithromycin |
| ||
OMP_AN:27868 |
OMP:0007249 |
decreased resistance to a chemical |
Relative to: OMP_AN:27510 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:27504) Mitomycin C |
| ||
OMP_AN:27869 |
OMP:0007879 |
decreased resistance to an antimicrobial agent |
Relative to: OMP_AN:27553 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:8642) Puromycin dihydrochloride |
| ||
OMP_AN:27870 |
OMP:0007896 |
decreased resistance to a surfactant |
Relative to: OMP_AN:27582 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:8984) SDS |
| ||
OMP_AN:27871 |
OMP:0007903 |
decreased resistance to bile acids |
Relative to: OMP_AN:27584 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CID:23687511) Taurocholic acid sodium salt hydrate |
| ||
OMP_AN:27872 |
OMP:0007249 |
decreased resistance to a chemical |
Relative to: OMP_AN:27567 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:28177) Theophylline anhydrous |
| ||
OMP_AN:27873 |
OMP:0007879 |
decreased resistance to an antimicrobial agent |
Relative to: OMP_AN:27588 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:164200) Triclosan/Irgasan |
| ||
OMP_AN:27874 |
OMP:0007879 |
decreased resistance to an antimicrobial agent |
Relative to: OMP_AN:27560 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CID:16219032) Bacitracin Zinc Sulfate |
| ||
OMP_AN:27875 |
OMP:0007879 |
decreased resistance to an antimicrobial agent |
Relative to: OMP_AN:27504 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:31924) Novobiocin sodium salt |
| ||
OMP_AN:27876 |
OMP:0007008 |
decreased population growth at acidic pH |
Relative to: OMP_AN:27622 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (**SID:329817955 SID:57651422) MES-HOMOPIPES |
| ||
OMP_AN:27877 |
OMP:0007879 |
decreased resistance to an antimicrobial agent |
Relative to: OMP_AN:27591 Genotype differences: +lacZ4787(del)( +surA765(del) -lacZ4787(del) Condition differences: no differences |
|
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
towards some (CHEBI:45924 + CHEBI:9331) Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331) |
| ||
Additional Information
Links
References
See Help:References for how to manage references in OMPwiki.
- ↑ Baba, T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2 2006.0008 PubMed OMPwiki page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 Nichols, RJ et al. (2011) Phenotypic landscape of a bacterial cell. Cell 144 143-56 PubMed OMPwiki page
o
- OMP:0006036 ! decreased resistance to macrolide
- OMP:0006037 ! increased resistance to macrolide
- OMP:0007008 ! decreased growth at acidic pH
- OMP:0007173 ! decreased resistance to antimicrobial peptide
- OMP:0007249 ! decreased resistance to a chemical
- OMP:0007879 ! decreased resistance to an antimicrobial agent
- OMP:0007896 ! decreased resistance to a surfactant
- OMP:0007903 ! decreased resistance to bile acids
- OMP:0007927 ! decreased anaerobic population growth