OMP ST:71125 ! Escherichia coli K-12 BW25113 glmS::SPA-kan

Strain Summary

Strain Name	Escherichia coli K-12 BW25113 glmS::SPA-kan
Synonyms
Taxon Information	Pangenome: Escherichia coli Subspecies and/or strain: K-12 NCBI Taxonomy ID: 83333
Genotype	DE(araD-araB)567 DE(rhaD-rhaB)568 F- Lambda- hsdR514 lacZ4787(del)(::rrnB-3) rph-1 glmS::SPA-kan
Strain Reference	PMID:21185072
Strain availability
Ancestry	parent:OMP ST:800 ! Escherichia coli K-12 BW25113
Annotated phenotypes
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Phenotype Annotation

Annotation ID	Qualifier	OMP ID	OMP term name	Relative phenotype information	Experimental condition	ECO ID	ECO term name	Reference	Annotation Extension	Notes
OMP_AN:37309		OMP:0006045	increased resistance to beta-lactam compound	Relative to: OMP_AN:27530 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Amoxicillin	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:2676) Amoxicillin	chemical concentration= 0.25 ug/ml normalized fitness= 3.66
OMP_AN:37310		OMP:0006044	decreased resistance to beta-lactam	Relative to: OMP_AN:27530 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Amoxicillin	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:2676) Amoxicillin	chemical concentration= 1.5 ug/ml normalized fitness= -4.82
OMP_AN:37311		OMP:0007896	decreased resistance to a surfactant	Relative to: OMP_AN:27581 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Benzalkonium chloride	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:3020) Benzalkonium chloride	chemical concentration= 25 ug/ml normalized fitness= -3.48
OMP_AN:37312		OMP:0006045	increased resistance to beta-lactam compound	Relative to: OMP_AN:27534 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Cefoxitin sodium hydrate	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:3501) Cefoxitin sodium hydrate	chemical concentration= 0.25 ug/ml normalized fitness= 6.47
OMP_AN:37313		OMP:0006044	decreased resistance to beta-lactam	Relative to: OMP_AN:27534 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Cefoxitin sodium hydrate	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:3501) Cefoxitin sodium hydrate	chemical concentration= 1 ug/ml normalized fitness= -4.59
OMP_AN:37314		OMP:0007249	decreased resistance to a chemical	Relative to: OMP_AN:27514 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Chlorpromazine hydrochloride	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:3649) Chlorpromazine hydrochloride	chemical concentration= 6 uM normalized fitness= -12.19
OMP_AN:37315		OMP:0007888	increased resistance to a metal	Relative to: OMP_AN:27579 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Copper stress-CuCl2 dihydrate	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:86318) Copper stress-CuCl2 dihydrate	chemical concentration= 1 mM (LB) normalized fitness= 3.84
OMP_AN:37316		OMP:0007376	increased resistance to an alkylating agent	Relative to: OMP_AN:27502 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:methyl methanesulfonate (MMS)	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:25255) methyl methanesulfonate (MMS)	chemical concentration= 0.05% normalized fitness= 4.5
OMP_AN:37317		OMP:0007886	decreased resistance to a metal	Relative to: OMP_AN:27580 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Nickel stress-Ni(II)Cl2 hexahydrate	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:53542) Nickel stress-Ni(II)Cl2 hexahydrate	chemical concentration= 1 mM (LB) normalized fitness= -7.05
OMP_AN:37318		OMP:0007879	decreased resistance to an antimicrobial agent	Relative to: OMP_AN:27553 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Puromycin dihydrochloride	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:8642) Puromycin dihydrochloride	chemical concentration= 5 ug/ml normalized fitness= -3.65
OMP_AN:37319		OMP:0007879	decreased resistance to an antimicrobial agent	Relative to: OMP_AN:27588 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Triclosan/Irgasan	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:164200) Triclosan/Irgasan	chemical concentration= 0.05 ug/ml normalized fitness= -8.39
OMP_AN:37320		OMP:0007520	increased population growth in high osmolarity	Relative to: OMP_AN:27595 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:NaCl	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:26710) NaCl	chemical concentration= 600 mM normalized fitness= 5.74
OMP_AN:37321		OMP:0006044	decreased resistance to beta-lactam	Relative to: OMP_AN:27538 Genotype differences: +lacZ4787(del)( +glmS -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Oxacillin sodium salt	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:52134) Oxacillin sodium salt	chemical concentration= 5 ug/ml normalized fitness= -6.47
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References

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