OMP ST:71030 ! Escherichia coli K-12 BW25113 fabZ(F101Y)-kan

Strain Summary

Strain Name	Escherichia coli K-12 BW25113 fabZ(F101Y)-kan
Synonyms	ECK0179-B-FABZ(F101Y)-KAN (Nichols et al. 2011. Supplemental Table S2)
Taxon Information	Pangenome: Escherichia coli Subspecies and/or strain: K-12 NCBI Taxonomy ID: 83333
Genotype	DE(araD-araB)567 DE(rhaD-rhaB)568 F- Lambda- hsdR514 lacZ4787(del)(::rrnB-3) rph-1 fabZ(F101Y)-kan
Strain Reference	PMID:21185072
Strain availability
Ancestry	parent:OMP ST:800 ! Escherichia coli K-12 BW25113
Annotated phenotypes
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Phenotype Annotation

Annotation ID	Qualifier	OMP ID	OMP term name	Relative phenotype information	Experimental condition	ECO ID	ECO term name	Reference	Annotation Extension	Notes
OMP_AN:37240		OMP:0006057	decreased resistance to aminoglycoside	Relative to: OMP_AN:27525 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Amikacin sulfate salt (disulfate)	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:2638) Amikacin sulfate salt (disulfate)	chemical concentration= 0.1 ug/ml normalized fitness= -3.86
OMP_AN:37241		OMP:0006044	decreased resistance to beta-lactam	Relative to: OMP_AN:27531 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Ampicillin	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:28971) Ampicillin	chemical concentration= 1 ug/ml normalized fitness= -3.84
OMP_AN:37242		OMP:0007879	decreased resistance to an antimicrobial agent	Relative to: OMP_AN:27552 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Azidothymidine	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:10110) Azidothymidine	chemical concentration= 1 ng/ml normalized fitness= -3.52
OMP_AN:37243		OMP:0007249	decreased resistance to a chemical	Relative to: OMP_AN:27592 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Calcofluor White M2R (F3543 Fluorescent Brightener 28)	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:50010) Calcofluor White M2R (F3543 Fluorescent Brightener 28)	chemical concentration= 50 ug/ml normalized fitness= -4.38
OMP_AN:37244		OMP:0007249	decreased resistance to a chemical	Relative to: OMP_AN:27512 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Hydroxyurea	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:44423) Hydroxyurea	chemical concentration= 10 mM normalized fitness= -3.96
OMP_AN:37245		OMP:0007886	decreased resistance to a metal	Relative to: OMP_AN:27580 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Nickel stress-Ni(II)Cl2 hexahydrate	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:53542) Nickel stress-Ni(II)Cl2 hexahydrate	chemical concentration= 1 mM (LB) normalized fitness= -3.4
OMP_AN:37246		OMP:0007879	decreased resistance to an antimicrobial agent	Relative to: OMP_AN:27564 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Phleomycin	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:75044) Phleomycin	chemical concentration= 0.2 ug/ml normalized fitness= -4.11
OMP_AN:37247		OMP:0006045	increased resistance to beta-lactam compound	Relative to: OMP_AN:27536 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Ceftazidime hydrate	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:3509) Ceftazidime hydrate	chemical concentration= 0.075 ug/ml normalized fitness= 3.16
OMP_AN:37248		OMP:0007879	decreased resistance to an antimicrobial agent	Relative to: OMP_AN:27558 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:D-Cycloserine	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:40009) D-Cycloserine	chemical concentration= 16 ug/ml normalized fitness= -3.69
OMP_AN:37249		OMP:0007520	increased population growth in high osmolarity	Relative to: OMP_AN:27595 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:NaCl	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:26710) NaCl	chemical concentration= 600 mM normalized fitness= 4
OMP_AN:37250		OMP:0007879	decreased resistance to an antimicrobial agent	Relative to: OMP_AN:27504 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Novobiocin sodium salt	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:31924) Novobiocin sodium salt	chemical concentration= 8 ug/ml normalized fitness= -8.42
OMP_AN:37251		OMP:0007008	decreased population growth at acidic pH	Relative to: OMP_AN:27622 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:MES-HOMOPIPES	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (**SID:329817955 SID:57651422) MES-HOMOPIPES	chemical concentration= pH 4 normalized fitness= -3.81
OMP_AN:37252		OMP:0006058	increased resistance to aminoglycoside	Relative to: OMP_AN:27527 Genotype differences: +lacZ4787(del)( +fabZ(F101Y)-kan -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Spectinomycin dihydrochloride pentahydrate	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072	towards some (CHEBI:9217) Spectinomycin dihydrochloride pentahydrate	chemical concentration= 4 ug/ml normalized fitness= 3.72
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References

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