Category:ECO:0000233 ! chromosome conformation capture evidence

name:chromosome conformation capture evidence
def:"A type of chromosome conformation capture-based evidence that is derived by performing a type of polymerase chain reaction (PCR) in the final product quantitation step." [ECO:MCC]
synonym:"3C" EXACT []
is_a:ECO:0000232 ! chromosome conformation capture-based evidence
comment:3C is used to study the structural properties and spatial organization of chromosomes inside cells. Like other types of chromosome conformation capture technology, 3C differs only in the fifth step, which involves performing either standard polymerase chain reaction (PCR) or quantitative PCR (qPCR) for product quantitation.