OMP ST:926 ! Escherichia coli K-12 JW5248

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Revision as of 12:54, 17 October 2016 by Kylliechang (talk | contribs) (Table edited by Kylliechang via TableEdit)

Strain Summary

Strain Name

Escherichia_coli_K-12_JW5248

Synonyms

BW25113 marR751(del)::kan, ECK1523

Taxon Information
  • Pangenome: Escherichia coli
  • Subspecies and/or strain: K-12
  • NCBI Taxonomy ID: 83333
Genotype

DE(araD-araB)567 DE(rhaD-rhaB)568 F- Lambda- hsdR514 lacZ4787(del)(::rrnB-3) rph-1 marR751(del)::kan

Strain Reference
Strain availability

CGSC

Ancestry

parent:OMP ST:800 ! Strain:Escherichia coli K-12 BW25113

Annotated phenotypes



Notes

Phenotype Annotation

Annotation ID not OMP ID OMP term name Relative phenotype information Experimental condition ECO ID ECO term name Reference Annotation Extension Notes

OMP_AN:666

OMP:0006045

increased resistance to beta-lactam compound

Relative to: OMP_AN:665


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:mecillinam (0.12 ug ml-1)

PMID:21185072[2]

CHEBI:51208 mecillinam

fitness score = 6.61

OMP_AN:667

OMP:0006068

increased resistance to chloramphenicol

Relative to: OMP_AN:649


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:chloramphenicol (2.0 ug ml-1)

PMID:21185072[2]

CHEBI:17698 chloramphenicol

fitness score = 5.13

OMP_AN:669

OMP:0006063

increased resistance to tetracycline

Relative to: OMP_AN:668


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:minocycline (1.0 ug ml-1)

PMID:21185072[2]

CHEBI:50694 minocycline

fitness score = 4.89

OMP_AN:671

OMP:0000334

increased resistance to aminopyrimidine

Relative to: OMP_AN:670


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:trimethoprim (0.2 ug ml-1)

PMID:21185072[2]

CHEBI:45924 trimethoprim

fitness score = 4.46

OMP_AN:672

OMP:0006063

increased resistance to tetracycline

Relative to: OMP_AN:647


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:tetracycline (1 ug ml-1)

PMID:21185072[2]

CHEBI:27902 tetracycline

fitness score = 4.22

OMP_AN:673

OMP:0006041

increased resistance to quinolone

Relative to: OMP_AN:653


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:streptonigrin (0.5 ug ml-1)

PMID:21185072[2]

CHEBI:9287 streptonigrin

fitness score = 4.09

OMP_AN:675

OMP:0006063

increased resistance to tetracycline

Relative to: OMP_AN:870


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:doxycycline (1.0 ug ml-1)

PMID:21185072[2]

CHEBI:50845 doxycycline

fitness score = 4.03

OMP_AN:676

OMP:0007384

increased resistance to a benzamide

Relative to: OMP_AN:659


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:CHIR-090 (0.075 ug ml-1)

PMID:21185072[2]

PubChem CID:11546620 Chir-090

fitness score = 3.93

OMP_AN:678

OMP:0006041

increased resistance to quinolone

Relative to: OMP_AN:677


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:ciprofloxacin (0.004 ug ml-1)

PMID:21185072[2]

CHEBI:100241 ciprofloxacin

fitness score = 3.70

OMP_AN:680

OMP:0007171

resistant to antimicrobial peptide

Relative to: OMP_AN:679


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:bleomycin (0.5 ug ml-1)

PMID:21185072[2]

CHEBI:22907 bleomycin

fitness score = 3.50

OMP_AN:682

OMP:0006037

increased resistance to macrolide

Relative to: OMP_AN:681


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:azithromycin (1.0 ug ml-1)

PMID:21185072[2]

CHEBI:2955 azithromycin

fitness score = 3.30

OMP_AN:684

OMP:0006037

increased resistance to macrolide

Relative to: OMP_AN:683


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:erythromycin (5.0 ug ml-1)

PMID:21185072[2]

CHEBI:48923 erythromycin

fitness score = 3.29

OMP_AN:686

OMP:0007136

resistant to alkaloid

Relative to: OMP_AN:685


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:MMS (0.05%)

PMID:21185072[2]

CHEBI:25255 MMS

fitness score = 8.56

OMP_AN:688

OMP:0007362

Increased resistance to a nucleoside

Relative to: OMP_AN:687


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:azidothymidine (1.0 ug ml-1)

PMID:21185072[2]

CHEBI:10110 azidothymidine

fitness score = 3.73

OMP_AN:690

OMP:0007249

Relative to: OMP_AN:689


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:propidium iodide (50 ug ml-1)

PMID:21185072[2]

CHEBI:51240 propidium iodide

fitness score = 5.15

OMP_AN:698

OMP:0006044

decreased resistance to beta-lactam

Relative to: OMP_AN:697


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:cefoxitin (0.5 ug ml-1)

PMID:21185072[2]

CHEBI:209807 cefoxitin

fitness score = -3.14

OMP_AN:700

OMP:0007219

decreased resistance to rifamycin

Relative to: OMP_AN:699


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:rifampicin (2.0 ug ml-1)

PMID:21185072[2]

CHEBI:28077 rifampicin

fitness score = -3.29

OMP_AN:816

OMP:0005276

decreased resistance to organic heterocyclic compound

Relative to: OMP_AN:815


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:A22 (15 ug ml-1)

PMID:21185072[2]

CID:16741200 A22

fitness score = -3.78

OMP_AN:819

decreased resistance to organic aromatic compound

Relative to: OMP_AN:817


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:procaine (30 ug ml-1)

PMID:21185072[2]

CHEBI:8430 procaine

fitness score = -3.39

OMP_AN:831

OMP:0007250

decreased sensitivity to a chemical

Relative to: OMP_AN:827


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:ethanol (2.0 ug ml-1)

PMID:21185072[2]

CHEBI:16236 ethanol

fitness score = -3.78

OMP_AN:832

OMP:0007250

decreased sensitivity to a chemical

Relative to: OMP_AN:828


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:bile 0.5%

PMID:21185072[2]

CHEBI:22868 bile

fitness score = -3.51

OMP_AN:833

OMP:0007250

decreased sensitivity to a chemical

Relative to: OMP_AN:829


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:glycerol

PMID:21185072[2]

CHEBI:17754 glycerol

fitness score = -3.45

OMP_AN:834

OMP:0007250

decreased sensitivity to a chemical

Relative to: OMP_AN:830


Genotype differences:

+marR751(del)


Condition differences:

no differences

medium:maltose

PMID:21185072[2]

CHEBI:17306 maltose

fitness score = -3.05



Additional Information

Links

References

See Help:References for how to manage references in OMPwiki.

  1. Baba, T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2 2006.0008 PubMed OMPwiki page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 2.20 2.21 2.22 Nichols, RJ et al. (2011) Phenotypic landscape of a bacterial cell. Cell 144 143-56 PubMed OMPwiki page