OMP ST:925 ! Escherichia coli K-12 JW5249

Strain Summary

Strain Name	Escherichia coli K-12 JW5249
Synonyms	BW25113 marA752(del)::FRT-kan-FRT, ECK1524, JW5249-1
Taxon Information	Pangenome: Escherichia coli Subspecies and/or strain: K-12 NCBI Taxonomy ID: 83333
Genotype	DE(araD-araB)567 DE(rhaD-rhaB)568 F- Lambda- hsdR514 lacZ4787(del)(::rrnB-3) rph-1 marA752(del)::kan
Strain Reference	other:Coli Genetic Stock Center PMID:16738554^[1]
Strain availability	Coli Genetic Stock Center
Ancestry	parent:OMP ST:800 ! Escherichia coli K-12 BW25113
Annotated phenotypes
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Annotation ID	OMP ID	OMP term name	Relative phenotype information	Experimental condition	ECO ID	ECO term name	Reference	Annotation Extension	Notes
OMP_AN:662	OMP:0006044	decreased resistance to beta-lactam	Relative to: OMP_AN:661 Genotype differences: +lacZ4787(del)( +marA752(del) -lacZ4787(del) Condition differences: no differences	medium:mecillinam (0.09 ug ml-1)			PMID:21185072^[2]	CHEBI:51208 mecillinam	fitness score = -4.00
OMP_AN:664	OMP:0007370	decreased resistance to an acridine	Relative to: OMP_AN:663 Genotype differences: +lacZ4787(del)( +marA752(del) -lacZ4787(del) Condition differences: no differences	medium:acriflavine (10 ug ml-1)			PMID:21185072^[2]	CHEBI:74728 acriflavine	fitness score = -3.59
OMP_AN:35900	OMP:0007249	decreased resistance to a chemical	Relative to: OMP_AN:27575 Genotype differences: +lacZ4787(del)( +marA752(del) -lacZ4787(del) Condition differences: no differences	temperature:37C medium:LB agar medium:Acriflavine (acriflavinium chloride)	ECO:0007005	high throughput direct assay evidence used in manual assertion	PMID:21185072^[2]	towards some (CHEBI:74728) Acriflavine (acriflavinium chloride)	chemical concentration= 2 ug/ml normalized fitness= -3.59
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↑ Baba, T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2 2006.0008 PubMed OMPwiki page
↑ ^2.0 ^2.1 ^2.2 Nichols, RJ et al. (2011) Phenotypic landscape of a bacterial cell. Cell 144 143-56 PubMed OMPwiki page