Difference between revisions of "PMID:2168148"

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Revision as of 11:41, 26 October 2012

Citation

Yoshida, H, Bogaki, M, Nakamura, M and Nakamura, S (1990) Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.Antimicrob. Agents Chemother. 34:1271-2

Abstract

Nucleotide sequence analysis of the gyrA genes of 10 spontaneous quinolone-resistant gyrA mutants of Escherichia coli KL16, including four mutants examined previously, disclosed that quinolone resistance was caused by a point mutation within the region between amino acids 67 and 106, especially in the vicinity of amino acid 83, of the GyrA protein.

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Keywords

4-Quinolones; Anti-Infective Agents; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Escherichia coli; Mutation

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Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

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