Difference between revisions of "PMID:400782"
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Increased resistance to rifampin. Table 2. | Increased resistance to rifampin. Table 2. | ||
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| + | a mutation or genetic difference within a strain | ||
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| + | *Taxon: Escherichia coli | ||
| + | *Strain: K-12 | ||
| + | *Substrain: EC3 | ||
| + | *NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&p=mapview&p=has_linkout&p=blast_url&p=genome_blast&lin=f&keep=1&srchmode=1&unlock 83333] | ||
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| + | *Genotype of Reference Strain: ''dnaA'' ''rpoB'' | ||
| + | *Genotype of Experimental Strain : ''dnaA46'' ''rpoB706'' in strain EC8 | ||
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| + | *Reference Condition: non permissive temp (42.5C) of the single mutant dnaA | ||
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| + | ''DnaA1'' Mutant is unable to grow at 42.5C, mutation in ''rpoB'' suppresses thermosensitivity allowing the strain to grow at 42.5C. | ||
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==Notes== | ==Notes== | ||
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| + | OMP term: | ||
| + | Mesophilic growth - term is being developed. | ||
| + | Rifampin- term being developed. | ||
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| + | Eco: | ||
| + | both in vitro assays | ||
==References== | ==References== | ||
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[[Category:Publication]] | [[Category:Publication]] | ||
| + | [[Category:LaRossa citations that need review]] | ||
Latest revision as of 17:44, 14 June 2013
| Citation |
Bagdasarian, MM, Izakowska, M and Bagdasarian, M (1977) Suppression of the DnaA phenotype by mutations in the rpoB cistron of ribonucleic acid polymerase in Salmonella typhimurium and Escherichia coli. J. Bacteriol. 130:577-82 |
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| Abstract |
A class of mutations that confer resistance to rifampin in Salmonella typhimurium and Escherichia coli also suppresses the thermosensitivity of chromosome initiation in dnaA mutants. Ribonucleic acid polymerase is resistant to rifampin in vitro in these suppressive mutants, and the suppressors of dnaA cannot be separated from the rpoB mutations by transduction. It is concluded, therefore, that certain rpoB mutations may suppress the DnaA phenotype. |
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Main Points of the Paper
Please summarize the main points of the paper.
- Mutations in rpoB suppress a dnaA phenotype.
Materials and Methods Used
Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).
Phenotype Annotations
See Help:AnnotationTable for details on how to edit this table.
| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
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a mutation or genetic difference within a strain |
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Increased resistance to rifampin. Table 2. |
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a mutation or genetic difference within a strain |
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DnaA1 Mutant is unable to grow at 42.5C, mutation in rpoB suppresses thermosensitivity allowing the strain to grow at 42.5C. |
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Notes
OMP term: Mesophilic growth - term is being developed. Rifampin- term being developed.
Eco: both in vitro assays
References
See Help:References for how to manage references in OMPwiki.
