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OMP ST:71245 ! Escherichia coli K-12 JW0052

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Rows in conflict with the working copy:

Annotation ID Qualifier OMP ID OMP term name Relative phenotype information Experimental condition ECO ID ECO term name Reference Annotation Extension Notes

public

OMP_AN:27863

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27575

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Acriflavine (acriflavinium chloride)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:74728) Acriflavine (acriflavinium chloride)

  • chemical concentration= 2 ug/ml
  • normalized fitness= -5.56

public

OMP_AN:27864

OMP:0007927

decreased anaerobic population growth

Relative to: OMP_AN:27618

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Anaerobic

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

  • normalized fitness= -4.8

public

OMP_AN:27865

OMP:0006036

decreased resistance to macrolide

Relative to: OMP_AN:27518

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Azithromycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:2955) Azithromycin

  • chemical concentration= 1 ug/ml
  • normalized fitness= -6.5

public

OMP_AN:27866

OMP:0007173

decreased resistance to host defense peptides

Relative to: OMP_AN:27562

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Cecropin B

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:16130488) Cecropin B

  • chemical concentration= 0.1 ug/ml
  • normalized fitness= -4.88

public

OMP_AN:27867

OMP:0006037

increased resistance to macrolide

Relative to: OMP_AN:27519

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Clarithromycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:3732) Clarithromycin

  • chemical concentration= 0.1 ug/ml
  • normalized fitness= 3.92

public

OMP_AN:27868

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27510

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Mitomycin C

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:27504) Mitomycin C

  • chemical concentration= 0.1 ug/ml
  • normalized fitness= -8.77

public

OMP_AN:27869

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27553

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Puromycin dihydrochloride

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8642) Puromycin dihydrochloride

  • chemical concentration= 5 ug/ml
  • normalized fitness= -4.5

public

OMP_AN:27870

OMP:0007896

decreased resistance to a surfactant

Relative to: OMP_AN:27582

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:SDS

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8984) SDS

  • chemical concentration= 0.5 %
  • normalized fitness= -11.66

public

OMP_AN:27871

OMP:0007903

decreased resistance to bile acids

Relative to: OMP_AN:27584

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Taurocholic acid sodium salt hydrate

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:23687511) Taurocholic acid sodium salt hydrate

  • chemical concentration= 0.5 %
  • normalized fitness= -4.6

public

OMP_AN:27872

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27567

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Theophylline anhydrous

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:28177) Theophylline anhydrous

  • chemical concentration= 100 ug/ml
  • normalized fitness= -5.65

public

OMP_AN:27873

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27588

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Triclosan/Irgasan

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:164200) Triclosan/Irgasan

  • chemical concentration= 0.05 ug/ml
  • normalized fitness= -3.71

public

OMP_AN:27874

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27560

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Bacitracin Zinc Sulfate

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:16219032) Bacitracin Zinc Sulfate

  • chemical concentration= 300 ug/ml
  • normalized fitness= -8.89

public

OMP_AN:27875

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27504

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Novobiocin sodium salt

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:31924) Novobiocin sodium salt

  • chemical concentration= 8 ug/ml
  • normalized fitness= -4.58

public

OMP_AN:27876

OMP:0007008

decreased population growth at acidic pH

Relative to: OMP_AN:27622

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:MES-HOMOPIPES

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (**SID:329817955 SID:57651422) MES-HOMOPIPES

  • chemical concentration= pH 4
  • normalized fitness= -14.8

public

OMP_AN:27877

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27591

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:45924 + CHEBI:9331) Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331)

  • chemical concentration= 0.1 + 50 ug/ml
  • normalized fitness= -4.36

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Annotation ID Qualifier OMP ID OMP term name Relative phenotype information Experimental condition ECO ID ECO term name Reference Annotation Extension Notes

public

OMP_AN:27863

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27575

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Acriflavine (acriflavinium chloride)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:74728) Acriflavine (acriflavinium chloride)

  • chemical concentration= 2 ug/ml
  • normalized fitness= -5.56

public

OMP_AN:27864

OMP:0007927

decreased anaerobic population growth

Relative to: OMP_AN:27618

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Anaerobic

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

  • normalized fitness= -4.8

public

OMP_AN:27865

OMP:0006036

decreased resistance to macrolide

Relative to: OMP_AN:27518

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Azithromycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:2955) Azithromycin

  • chemical concentration= 1 ug/ml
  • normalized fitness= -6.5

public

OMP_AN:27866

OMP:0007173

decreased resistance to host defense peptides

Relative to: OMP_AN:27562

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Cecropin B

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:16130488) Cecropin B

  • chemical concentration= 0.1 ug/ml
  • normalized fitness= -4.88

public

OMP_AN:27867

OMP:0006037

increased resistance to macrolide

Relative to: OMP_AN:27519

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Clarithromycin

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:3732) Clarithromycin

  • chemical concentration= 0.1 ug/ml
  • normalized fitness= 3.92

public

OMP_AN:27868

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27510

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Mitomycin C

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:27504) Mitomycin C

  • chemical concentration= 0.1 ug/ml
  • normalized fitness= -8.77

public

OMP_AN:27869

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27553

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Puromycin dihydrochloride

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8642) Puromycin dihydrochloride

  • chemical concentration= 5 ug/ml
  • normalized fitness= -4.5

public

OMP_AN:27870

OMP:0007896

decreased resistance to a surfactant

Relative to: OMP_AN:27582

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:SDS

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:8984) SDS

  • chemical concentration= 0.5 %
  • normalized fitness= -11.66

public

OMP_AN:27871

OMP:0007903

decreased resistance to bile acids

Relative to: OMP_AN:27584

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Taurocholic acid sodium salt hydrate

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:23687511) Taurocholic acid sodium salt hydrate

  • chemical concentration= 0.5 %
  • normalized fitness= -4.6

public

OMP_AN:27872

OMP:0007249

decreased resistance to a chemical

Relative to: OMP_AN:27567

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Theophylline anhydrous

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:28177) Theophylline anhydrous

  • chemical concentration= 100 ug/ml
  • normalized fitness= -5.65

public

OMP_AN:27873

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27588

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Triclosan/Irgasan

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:164200) Triclosan/Irgasan

  • chemical concentration= 0.05 ug/ml
  • normalized fitness= -3.71

public

OMP_AN:27874

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27560

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Bacitracin Zinc Sulfate

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CID:16219032) Bacitracin Zinc Sulfate

  • chemical concentration= 300 ug/ml
  • normalized fitness= -8.89

public

OMP_AN:27875

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27504

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Novobiocin sodium salt

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:31924) Novobiocin sodium salt

  • chemical concentration= 8 ug/ml
  • normalized fitness= -4.58

public

OMP_AN:27876

OMP:0007008

decreased population growth at acidic pH

Relative to: OMP_AN:27622

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:MES-HOMOPIPES

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (**SID:329817955 SID:57651422) MES-HOMOPIPES

  • chemical concentration= pH 4
  • normalized fitness= -14.8

public

OMP_AN:27877

OMP:0007879

decreased resistance to an antimicrobial agent

Relative to: OMP_AN:27591

Genotype differences:

+lacZ4787(del)( +surA765(del) -lacZ4787(del)

Condition differences:

no differences

  • temperature:37C
  • medium:LB agar
  • medium:Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331)

ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072

towards some (CHEBI:45924 + CHEBI:9331) Trimethoprim (CHEBI:45924) + Sulfamethizole (CHEBI:9331)

  • chemical concentration= 0.1 + 50 ug/ml
  • normalized fitness= -4.36
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