E. coli-to-Cancer Gene-function Atlas (ECGA)

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This data browser queries data from

Jun Xia*, Li-Ya Chiu*, Ralf B. Nehring, María Angélica Bravo Núñez, Qian Mei, Mercedes Perez, Yin Zhai, Devon M. Fitzgerald, John P. Pribis, Yumeng Wang, Chenyue W. Hu, Reid T. Powell, Sandra A. LaBonte, Ali Jalali, Meztli L. Matadamas Guzmán, Alfred M. Lentzsch, Adam T. Szafran, Mohan C. Joshi, Megan Richters, Janet L. Gibson, Ryan L. Frisch, P.J. Hastings, David Bates, Christine Queitsch, Susan G. Hilsenbeck, Cristian Coarfa, James C. Hu, Deborah A. Siegele, Kenneth L. Scott, Han Liang, Michael A. Mancini, Christophe Herman§, Kyle M. Miller§ & Susan M. Rosenberg§,Bacteria-to- human protein networks reveal origins of endogenous DNA damage.

https://www.cell.com/cell/fulltext/S0092-8674(18)31622-2

Shee et al. 2013 eLIFE [1] Xia et al. 2016 Science Advances [2]

  1. Shee, C et al. (2013) Engineered proteins detect spontaneous DNA breakage in human and bacterial cells. Elife 2 e01222 PubMed OMPwiki page
  2. Xia, J et al. (2016) Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase. Sci Adv 2 e1601605 PubMed OMPwiki page


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Select which fields you would like to display: Note: Only the Ecoli genes are clustered and have mutation rates. Only the Human genes have Subcellular localization of N-terminal GFP fusion and Copy-number increase in cancers


 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Brief table explanation for users.

GeneProductDDP PhenotypesFunctionGene HomologsClusterNormalized mutation rateSubcellular localization of N-terminal GFP fusionCopy-number increase in cancers?Has a human analog?DNA damage quenched by thiourea?
aaeRHTH-type transcriptional activator PhleoTranscription regulation-DNA binding TF3Y
aegAPutative oxidoreductase- Fe-S subunitPhleo, H2O2oxidation reductionAIFM3, DLD, DPYD, FDXR1Y
aroPAromatic amino acid transport proteinPhleo, H2O2, AC, ROSTransporterSLC7A1, SLC7A11, SLC7A14, SLC7A2, SLC7A3, SLC7A4, SLC7A6, SLC7A7, SLC7A8, SLC7A92YN
ascGHTH-type transcriptional regulator Phleo, H2O2, RF, ROSTranscription regulation-DNA binding TF1YN
atpDATP synthase subunit betaPhleo, DSB, RFMetabolism1Y
bssSBiofilm regulator BssSPhleo, RF, ACVarious cellular processes6Y
cbtACytoskeleton-binding toxin Phleo, RF, ROSVarious cellular processes6
cheAChemotaxis proteinPhleo, DSB, RFVarious cellular processes-two component systemPDK26Y
choDNA endonuclease Phleo, H2O2, RFDNA repair1Y
cobSAdenosylcobinamide-GDP ribazoletransferasePhleo, DSBMetabolism3
csgDCsgBAC operon transcriptional regulatory proteinPhleo, H2O2, DSB, RF, ACTranscription regulation-DNA binding TF27.6Y
cusRTranscriptional regulatory protein Phleo, MMC, RF, ACTranscription regulation-DNA binding TF6Y
cyoEProtoheme IX farnesyltransferasePhleo, DSB, RFoxidation reductionCOQ2, COX106Y
dcmDNA-cytosine methyltransferasePhleo, RFDNA replicationDNMT1, TRDMT16Y
ddpDProbable DD-dipeptide transport ATP-binding proteinPhleo, RF, ACTransporter-ABC transporter6Y
degQPeriplasmic pH-dependent serine endoprotease PhleoVarious cellular processes3
diaADnaA initiator-associating proteinPhleo, H2O2, AC, ROSDNA replication2YY
dinBDNA polymerase IVPhleo, H2O2, AC, ROSDNA replicationPOLH, POLI, POLK, REV12Y
dinDDNA-damage-inducible protein DPhleo, DSB, RF, ACDNA repair64.5Y
dinGProbable ATP-dependent helicasePhleo, H2O2, MMC, ACDNA repairBRIP12Y
dnaBReplicative DNA helicasePhleo, H2O2, DSB, RF, AC, ROSDNA replication2Y
dnaXDNA polymerase III subunit tauPhleo, DSB, ACDNA replicationRFC2, RFC3, RFC4, RFC56Y
dusCtRNA-dihydrouridine(16) synthasePhleooxidation reduction3Y
eutMEthanolamine utilization protein Phleo, AC, ROSMetabolism6Y
evgAPositive transcription regulator Phleo, RF, AC, ROSTranscription regulation-DNA binding TF6YY
exuTHexuronate transporterPhleo, DSB, RFTransporterSLC17A1, SLC17A2, SLC17A3, SLC17A4, SLC17A5, SLC17A6, SLC17A7, SLC17A8, SLC17A9, SLC37A4, SPNS1, SPNS23Y
fdnGFormate dehydrogenase- nitrate-inducible major subunitPhleooxidation reduction6Y
fieFFerrous-iron efflux pump PhleoTransporter3Y
fliFFlagellar M-ring proteinPhleo, H2O2, DSBMetabolism1
glcCGlc operon transcriptional activatorPhleoTranscription regulation-DNA binding TF3Y
glgAGlycogen synthasePhleo, ACMetabolism3
guaDGuanine deaminasePhleo, RF, ROSMetabolism6YY
gyrBDNA gyrase subunit BPhleoDNA replication3Y
hdaDnaA regulatory inactivatorPhleo, H2O2, DSB, AC, ROSDNA replication2YN
hemXPutative uroporphyrinogen-III C-methyltransferasePhleo, ACMetabolism3Y
hiuH5-hydroxyisourate hydrolasePhleo, H2O2Metabolism1Y
hypFCarbamoyltransferase Phleo, DSB, RFMetabolismYRDC61.0Y
kdpDSensor proteinPhleo, H2O2, DSBVarious cellular processes-two component system2Y
manZMannose permease IID componentPhleo, H2O2, ROSMetabolism2N
mdtAMultidrug resistance protein Phleo, DSBTransporter3Y
metGMethionine--tRNA ligasePhleo, MMCVarious cellular processes-protein biosynthesisAIMP1, DARS, DARS2, IARS2, LARS, LARS2, MARS, MARS2, YARS3Y
mhpE4-hydroxy-2-oxovalerate aldolasePhleo, H2O2, DSB, RF, ROSMetabolismHMGCL, HMGCLL12YY
mokCHokC regulatory proteinPhleo, H2O2, RF, AC, ROSVarious cellular processes2N
mutSDNA mismatch-repair protein- mismatch recognitionPhleo, H2O2, DSB, ACDNA repairMSH2, MSH3, MSH4, MSH5, MSH62Y
nanTPutative sialic acid transporterPhleo, DSB, RF, ROSTransporterSLC16A1, SLC22A1, SLC22A10, SLC22A13, SLC22A16, SLC22A2, SLC22A6, SLC22A8, SLC2A10, SLC2A12, SLC2A13, SPNS1, SPNS2, SV2A, SV2B, SVOP, SVOPL6YY
nlpILipoprotein Phleo, AC, ROSVarious cellular processes-cell division2YN
nudCNADH pyrophosphatasePhleo, H2O2, RF, ACMetabolism1Y
panE2-dehydropantoate 2-reductasePhleo, RF, ACMetabolism6
polADNA polymerase IPhleo, H2O2, DSBDNA replicationPOLN, POLQ1Y
polBDNA polymerase IIPhleo, H2O2, MMC, DSB, RFDNA replicationPOLA1, POLD1, POLE, REV3L1Y
ppiCPeptidyl-prolyl cis-trans isomerase CPhleo, RFMetabolismPIN1, PIN43Y
prfBPeptide chain release factor 2Phleo, H2O2, RF, ROSVarious cellular processes-protein biosynthesisC12orf65, MTRF1, MTRF1L2YN
prpD2-methylcitrate dehydratasePhleoMetabolismIRG13Y
rbsDD-ribose pyranasePhleoMetabolismFUOM3
recQATP-dependent DNA helicase Phleo, H2O2, MMC, DSBDNA repairBLM, RECQL41Y
recRHomologous recombination (HR) proteinPhleo, RFDNA repair and SOS DDR3Y
rffHGlucose-1-phosphate thymidylyltransferase 2Phleo, RFMetabolismEIF2B3, GMPPA, GMPPB3
rhmTInner membrane transport protein PhleoTransporter6Y
rusACrossover junction endodeoxyribonucleasePhleo, DSB, RF, ACDNA repair65.0Y
ruvAHolliday-junction recognition protein ATP-dependent DNA helicase Phleo, AC, ROSDNA repair2YN
seqANegative modulator of initiation of replicationPhleo, H2O2, DSB, AC, ROSDNA replication2Y
ssbSingle-stranded DNA-binding proteinPhleo, H2O2DNA replicationSSBP11Y
sstTSerine/threonine transporterPhleo, DSB, RFTransporterSLC1A1, SLC1A3, SLC1A51
thiItRNA sulfurtransferasePhleo, DSB, ACMetabolism3Y
thiMHydroxyethylthiazole kinasePhleoMetabolism3
topBDNA topoisomerase 3PhleoDNA replicationTOP3A, TOP3B313.8Y
uspGUniversal stress protein G- stress responsePhleo, H2O2, DSB, ACVarious cellular processes1Y
waaA3-deoxy-D-manno-octulosonic acid transferasePhleo, DSB, ACMetabolism3
waaFADP-heptose--LPS heptosyltransferase 2Phleo, RF, ACMetabolism6
waaHUDP-glucuronate:LPS(HepIII) glycosyltransferasePhleo, DSB, RF, AC, ROSMetabolismALG5, B3GNTL1, DPM1, GALNT86YN
yafZHypothetical protein- unknown functionPhleo, H2O2, RF, ACUnknown1
yagLUnknown functionPhleo, H2O2, DSB, RF, AC, ROSUnknown2
yajRUnknown function- inner-membrane transport protein similarityPhleo, H2O2, DSBUnknownMFSD10, MFSD8, MFSD9, SLC18A2126.3Y
ybaQUncharacterized HTH-type transcriptional regulator Phleo, RFTranscription regulation-DNA binding TF6Y
ybbPSulfur transfer proteinPhleo, RF, ROSTransporter6YN
ybgQUnknown function- outer-membrane usher protein similarityPhleo, H2O2Unknown135.0
yccTUnknown function- conserved proteinPhleo, RFUnknown3
ydcRUncharacterized HTH-type transcriptional regulatorPhleo, H2O2, DSB, RFTranscription regulation-DNA binding TFAADAT, ACCS, ACCSL, BCKDK, CCBL1, CCBL2, PDK1, PDK2, PDK3, PDK4, SLC18A3, SLC22A13, SLC22A8, SV2A, TAT, TOP2A, TOP2B16.0Y
ydfCUnknown functionPhleo, RF, ACUnknown6
ydhBUncharacterized HTH-type transcriptional regulator Phleo, H2O2, DSBTranscription regulation-DNA binding TF1Y
ydhCUnknown function- inner membrane transport protein similarityPhleo, RFUnknownSLC18A33Y
ydjMInner-membrane protein similarity- up-regulated by SOS DNA-damage responsePhleo, H2O2, RFUnknown1Y
ydjYUnknown functionPhleo, H2O2, MMC, DSB, RF, AC, ROSUnknown2N
yeaOUnknown functionPhleo, H2O2, AC, ROSUnknown2Y
yecEUnknown function- conserved proteinPhleoUnknown3
yedAUncharacterized- inner membrane transporter similarityPhleo, H2O2Unknown10.4Y
yedIUnknown function- inner membrane proteinPhleo, ROSUnknown6YY
yedQProbable diguanylate cyclasePhleo, H2O2Metabolism1Y
yegIUnknown functionPhleo, DSB, AC, ROSUnknown617.5
yehIUnknown functionPhleoUnknown3
yehSUnknown functionPhleo, H2O2, MMCUnknown1
yfaQUnknown functionPhleo, RFUnknown3
yfeDUnknown functionPhleo, RF, AC, ROSUnknown6N
yfjSUnknown function- putative lipoproteinPhleo, H2O2, RF, AC, ROSUnknown2YN
yhbSUnknown function- N-acetyltransferase similarityPhleo, AC, ROSUnknownNAT8B2YN
yhcBInner membrane protein Phleo, RF, AC, ROSoxidation reduction6YN
yhdPUnknown functionPhleo, H2O2, DSBUnknown1
yhgAUnknown functionPhleo, H2O2, RFUnknown1
yicRUnknown function- hypothetical proteinPhleo, DSB, RFUnknown6
yiiMUnknown function- putative protein involved in base-analog detoxificationPhleoUnknown3Y
yliFUnknown function- putative lipoproteinPhleo, H2O2, MMC, RFUnknown1Y
ynjCUnknown function- inner membrane ABC transporter permease similarityPhleo, DSB, RFTransporter-ABC transporter3Y
ypdBTranscriptional regulatory protein Phleo, H2O2, DSB, RFTranscription regulation-DNA binding TF6Y
ypdFUnknown function- aminopeptidase similarityPhleo, DSB, RF, AC, ROSUnknown2YY
yqgEUnknown function- putative proteinPhleoUnknown3
yqjDUnknown functionPhleo, RFUnknown3
arcBAerobic respiration control sensor protein H2O2, RFMetabolism1Y
bamCOuter membrane protein assembly factor H2O2, DSBVarious cellular processes1Y
basRTranscriptional regulatory protein H2O2Transcription regulation-DNA binding TF1Y
cadALysine decarboxylase- inducibleH2O2, RFMetabolism55.5, 5.5Y
corAMagnesium transport protein H2O2, DSB, RF, AC, ROSTransporter516.3YY
entSEnterobactin exporter H2O2, DSBTransporter1Y
eutPUnknown function- ethanolamine utilization protein similarityH2O2, MMC, DSBUnknown1
fsaBFructose-6-phosphate aldolase 2H2O2Metabolism1Y
ftsKDNA translocase-chromosome segregationH2O2, DSB, RF, AC, ROSVarious cellular processes-cell divisionMACF15YN
hcaRHca operon transcriptional activatorH2O2, DSB, RF, ACTranscription regulation-DNA binding TF51.9Y
hslUH2O2, DSB, ACVarious cellular processesAFG3L2, ATAD1, CLPB, CLPX, FIGNL1, PSMC2, PSMC4, PSMC5, PSMC6, SPG7, YME1L137.8Y
leuOHTH-type transcriptional regulatorH2O2Transcription regulation-DNA binding TF111.4Y
lhrProbable ATP-dependent helicase H2O2, RFDNA replicationASCC3, DDX20, DDX21, DDX27, DDX3X, DDX50, DDX52, DDX54, DDX59, DDX60, DDX60L, EIF4A2, HELQ, HFM1, POLQ, RECQL4, SKIV2L, SKIV2L2, SNRNP200, WRN1Y
macBMacrolide export ATP-binding/permease protein H2O2, DSB, RFTransporter-ABC transporterABCA1, ABCA10, ABCA12, ABCA13, ABCA2, ABCA3, ABCA4, ABCA5, ABCA6, ABCA7, ABCA8, ABCA9, ABCB1, ABCB10, ABCB11, ABCB4, ABCB5, ABCB6, ABCB7, ABCB8, ABCB9, ABCC1, ABCC10, ABCC11, ABCC12, ABCC2, ABCC3, ABCC4, ABCC5, ABCC6, ABCC8, ABCC9, ABCD2, ABCD3, ABCD4, ABCE1, ABCF1, ABCF2, ABCF3, ABCG1, ABCG2, ABCG4, ABCG5, ABCG8, CFTR, TAP1, TAP251.8Y
mcrA5-methylcytosine-specific restriction enzyme AH2O2, RFVarious cellular processes-DNA endonuclease5Y
mhpRMhp operon transcriptional activatorH2O2, DSB, RF, ACTranscription regulation-DNA binding TF5137.5Y
plaPLow-affinity putrescine importer H2O2, DSB, ROSTransporter5YY
rarAReplication-associated recombination protein AH2O2, DSB, RFDNA repair and replicationAFG3L2, CHTF18, FIGNL1, NSF, NVL, PEX1, PSMC1, PSMC2, PSMC4, PSMC5, PSMC6, RFC2, RFC4, RFC5, SPAST, SPATA5L1, VPS4A, VPS4B, WRNIP15Y
recNRecombinational DNA repair proteinH2O2, RFDNA repair1Y
tatBSec-independent protein translocase protein H2O2, DSB, RF, ROSTransporter5YY
topADNA topoisomerase 1H2O2, DSB, RF, AC, ROSDNA replicationTOP3A, TOP3B5Y
uvrBNucleotide excision repair (NER) protein- DNA-damage recognitionH2O2, RF, ROSDNA repairDDX17, DDX19A, DDX19B, DDX21, DDX25, DDX4, DDX41, DDX42, DDX5, DDX50, DDX52, DDX59, EIF4A1, EIF4A2, EIF4A3, FANCM, IFIH1520.0Y
uvrDDNA helicase II- used in mismatch repair NER anti-RecA/HRH2O2, DSB, ACDNA repairPARPBP1Y
yadDUnknown functionH2O2, DSB, RF, ROSUnknown5
yafVUnknown function- hydrolase similarityH2O2UnknownNIT1, NIT25Y
ybaMUnknown functionH2O2, DSB, RFUnknown5
yeaWPutative dioxygenase subunit alpha H2O2, DSB, RF, ROSoxidation reduction5YN
yfeRUncharacterized HTH-type transcriptional regulator H2O2, DSB, RF, ACTranscription regulation-DNA binding TF5Y
yhfKUnknown functionH2O2Unknown1
yhgEUnknown functionH2O2, RF, AC, ROSUnknown2N
ykgM50S ribosomal protein L31 type BH2O2, DSB, RF, ACVarious cellular processes-protein biosynthesis5Y
yoaAUnknown function- probable ATP-dependent helicaseH2O2, DSBUnknownBRIP1, ERCC25Y
cueOBlue copper oxidaseMMC, DSBoxidation reduction30.5Y
cusACation efflux system protein DSB, RFTransporter3Y
dnaAChromosomal replication initiator protein DSB, RFDNA replication3Y
fluAntigen 43DSB, ROSTransporter3YN
folDBifunctional protein DSBoxidation reduction38.1Y
grpENucleotide exchange factorDSB, RFVarious cellular processesGRPEL1, GRPEL2620.0Y
hsdRType I restriction enzyme EcoKI R DNA endonucleaseDSB, AC, ROSVarious cellular processes-DNA endonucleasePPFIA1, PPFIA23YY
pepNAminopeptidase NDSB, RFMetabolismANPEP, ENPEP, ERAP1, ERAP2, LNPEP, LTA4H, NPEPPS, RNPEP, RNPEPL1, TRHDE1Y
pgrRHTH-type transcriptional regulator DSB, RF, ACTranscription regulation-DNA binding TF333.8Y
pinEDNA-invertase from lambdoid prophage e14DSB, AC, ROSVarious cellular processes3YN
recFDNA replication and repair protein DSBDNA repair and SOS DDR3Y
spoTBifunctional (p)ppGpp synthase/hydrolase- stringent responseDSB, RF"Metabolism-stress responseHDDC33Y
thiGThiazole synthaseDSB, RF, ACMetabolism3Y
tufBTranslation elongation factor Tu 2DSB, RFMetabolismEEF1A1, EEF1A2, EEF2, EEFSEC, EFTUD1, EFTUD2, EIF2S3, EIF5B, GFM1, GFM2, GSPT1, GSPT2, GTPBP1, GTPBP2, GUF1, HBS1L, MTIF2, TUFM3Y
uvrANER protein- DNA-damage recognitionDSB, RFDNA repairABCA1, ABCB1, ABCB10, ABCB11, ABCB4, ABCB5, ABCB8, ABCC1, ABCC12, ABCC4, ABCC6, ABCC8, ABCC9, ABCE1, ABCG2, ABCG83Y
xanQXanthine permeaseDSB, AC, ROSTransporter3YY
xdhAXanthine dehydrogenase molybdenum-binding subunitDSB, RF, ROSMetabolism3YN
yahBUncharacterized HTH-type transcriptional regulatorDSB, RFTranscription regulation-DNA binding TF6Y
ybaOUncharacterized HTH-type transcriptional regulatorDSBTranscription regulation-DNA binding TF3Y
ybbYUnknown function- putative purine permeaseDSB, RFUnknownSLC23A1, SLC23A26
yciTUncharacterized HTH-type transcriptional regulator DSB, RFTranscription regulation-DNA binding TF3Y
ydfUUnknown functionDSBUnknown31.4
yhcMCell-division protein with ATPase activityDSBVarious cellular processes-cell divisionLACE13Y
yhiMUnknown function- inner membrane protein similarityDSB, RF, AC, ROSUnknown3YN
yihWUncharacterized HTH-type transcriptional regulator DSB, ACTranscription regulation-DNA binding TF5Y
yjjJUnknown function- putative kinaseDSB, AC, ROSUnknown3Y
ykgAPutative HTH-type transcriptional regulatorDSB, RFTranscription regulation-DNA binding TF3Y
damDNA adenine methylaseRFDNA replication3Y
dppDDipeptide transport ATP-binding protein RFTransporter-ABC transporterABCA1, ABCA10, ABCA12, ABCA13, ABCA2, ABCA3, ABCA4, ABCA5, ABCA6, ABCA7, ABCA8, ABCA9, ABCB1, ABCB10, ABCB11, ABCB4, ABCB5, ABCB6, ABCB7, ABCB8, ABCB9, ABCC1, ABCC10, ABCC11, ABCC12, ABCC2, ABCC4, ABCC5, ABCC8, ABCC9, ABCF1, ABCF2, ABCF3, ABCG1, ABCG2, ABCG4, ABCG5, ABCG8, CFTR, TAP1, TAP23Y
dsbGThioldisulfide interchange protein RFoxidation reduction31.1Y
ftsXCell-division protein RF, AC, ROSVarious cellular processes-cell division3YN
iapAlkaline phosphatase isozyme conversion proteinRFVarious cellular processes3Y
mrrMrr restriction system proteinRF, AC, ROSVarious cellular processes-DNA endonuclease395.0Y
ORF6106.1Unknown functionRFUnknown31.6
rplT50S ribosomal protein L20RFVarious cellular processes-protein biosynthesisMRPL203Y
sbcCDNA endo-exonuclease SbcCD subunit CRF, ACDNA repairSMC1A, SMC23Y
smgUnknown functionRFUnknown3
speABiosynthetic arginine decarboxylaseRF, ROSMetabolism6Y
speCOrnithine decarboxylase- constitutiveRFMetabolism3Y
tasPredicted oxidoreductase- NADP(H)-dependent aldo-keto reductaseRF, ROSoxidation reductionAKR1A1, AKR1B10, AKR1B15, AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1D1, AKR1E2, AKR7A2, AKR7A3, KCNAB1, KCNAB2, KCNAB33YN
trpEAnthranilate synthase component 1RFMetabolism3
yafYUnknown function- lipoprotein similarityRF, AC, ROSUnknown3YN
yddGUnknown function- aromatic amino acid exporter similarityRFUnknown38.1Y
yhiiUnknown function- putative uncharacterized proteinRFUnknown3
ynfGUnknown function- probable anaerobic dimethyl sulfoxide reductase chainRF, AC, ROSUnknown3N
ydfKUnknown functionAC, ROSUnknown3Y
yidPUncharacterized HTH-type transcriptional regulator ACTranscription regulation-DNA binding TF3Y
yihIDer GTPase-activating proteinACVarious cellular processes3Y
hemAGlutamyl-tRNA reductaseROSoxidation reductionCRYM3YY
hnsDNA-binding protein H-NSROS, DSB, AC, H2O2Transcription regulation-DNA binding TF3Y
zipACell-division protein ROSVarious cellular processes-cell divisionTTN312.3YY
ampGAmpG muropeptide MFS transporterTransporterMFSD3, SLC33A13Y
nikCNickel transport system permease protein Transporter3Y
exoXDNA 3?- single-strand Exonuclease 10 functions in mismatch repairDNA repair3Y
hemGProtoporphyrinogen IX dehydrogenase [menaquinone]oxidation reduction3Y
hhaHemolysin expression-modulating proteinTranscription regulation3Y
lepBSignal peptidase IVarious cellular processes-protein biosynthesisIMMP1L3Y
mdtBMultidrug resistance protein Transporter32.9
mutMFormamidopyrimidine-DNA glycosylaseDNA repairNEIL1, NEIL2, NEIL33Y
pdhRPyruvate dehydrogenase complex repressorMetabolism3Y
pflFPutative pyruvate formate lyaseMetabolism3Y
ppcPhosphoenolpyruvate carboxylaseMetabolism3
ptsNNitrogen regulatory proteinMetabolism3Y
setBSugar efflux transporter BTransporter33.6Y
sfsASugar fermentation stimulation protein AVarious cellular processes311.6
waaNmyristoyl-acyl carrier protein (ACP)-dependent acyltransferaseVarious cellular processes3Y
yehHPutative molybdate metabolism regulatorMetabolism3
yejHUnknown functionUnknownERCC3, FANCM, IFIH1, RECQL3
yijFUnknown functionUnknown31.8
dosOxygen sensor proteinTranscription regulation6Y