PMID:4939769
| Citation |
Dempsey, WB and Arcement, LJ (1971) Identification of the forms of vitamin B 6 present in the culture media of "vitamin B 6 control" mutants.J. Bacteriol. 107:580-2 |
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| Abstract |
An Escherichia coli mutant resistant to isoniazid (WG497) contained 0.6 mumole of extracellular pyridoxamine and pyridoxamine phosphate in the early stationary phase. A suppressed lysine mutant (AT1024) contained 1.4 mumoles of pyridoxal phosphate under the same conditions. The internal concentration of vitamin B(6) was one-half of normal for AT1024 and increased fivefold for WG497. |
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| Keywords |
Biological Assay; Cell Membrane Permeability; Cell-Free System; Culture Media; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Isoniazid; Mutation; Picolines; Pyridoxal Phosphate; Pyridoxine; Toluene; Yeasts |
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Main Points of the Paper
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Materials and Methods Used
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Phenotype Annotations
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| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
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a mutation or genetic difference within a strain |
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OMP:0000276 |
increased resistance to antimicrobial compound |
ECO:0000182 |
in vitro culture assay data |
Resistant to Isoniazid |
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Notes
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