Difference between revisions of "OMP ST:74667 ! Virtual reference strain for Nichols RJ (2011) Cell 144, 143-156."

From OMPwiki
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(Table edited by $2 via TableEdit)
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|
 
|
 
concentrations of SDS used were (0.5, 1, 2, 3, or 4%)  
 
concentrations of SDS used were (0.5, 1, 2, 3, or 4%)  
|-
 
|
 
OMP_AN:27432
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Trimethoprim
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:45924) Trimethoprim
 
|
 
0.1, 0.2, 0.3, 0.4 ug/ml
 
|-
 
|
 
OMP_AN:27433
 
|
 
 
|
 
OMP:0007247
 
|
 
resistant to a chemical
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Dibucaine
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:247956) Dibucaine
 
|
 
0.4, 0.8, 1.2 mM
 
|-
 
|
 
OMP_AN:27434
 
|
 
 
|
 
OMP:0007373
 
|
 
resistant to alkylating agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:methyl methanesulfonate (MMS)
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:25255) methyl methanesulfonate (MMS)
 
|
 
0.05%
 
|-
 
|
 
OMP_AN:27435
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Nitrofurantoin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:71415) Nitrofurantoin
 
|
 
0.1, 0.5, 1, 1.5, 2 ug/ml
 
|-
 
|
 
OMP_AN:27436
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Novobiocin sodium salt
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:31924) Novobiocin sodium salt
 
|
 
4, 6, 8, 10, 12, 30 ug/ml
 
|-
 
|
 
OMP_AN:27437
 
|
 
 
|
 
OMP:0007247
 
|
 
resistant to a chemical
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Methotrexate hydrate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:165528) Methotrexate hydrate
 
|
 
1, 25 ug/ml
 
|-
 
|
 
OMP_AN:27438
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Doxorubicin hydrochloride
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:31522) Doxorubicin hydrochloride
 
|
 
1, 10 ug/ml
 
|-
 
|
 
OMP_AN:27439
 
|
 
 
|
 
OMP:0007909
 
|
 
resistant to a chelator
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:EDTA disodium salt dihydrate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:64758) EDTA disodium salt dihydrate
 
|
 
0.1,  0.5,  1 mM
 
|-
 
|
 
OMP_AN:27440
 
|
 
 
|
 
OMP:0007909
 
|
 
resistant to a chelator
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:EGTA
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:30740) EGTA
 
|
 
0.1,  0.5,  1,  2 mM
 
|-
 
|
 
OMP_AN:27441
 
|
 
 
|
 
OMP:0007247
 
|
 
resistant to a chemical
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Cisplatin-cis-Diamineplatinum(II) dichloride
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:27899) Cisplatin-cis-Diamineplatinum(II) dichloride
 
|
 
20, 50, 100 ug/ml
 
|-
 
|
 
OMP_AN:27442
 
|
 
 
|
 
OMP:0007247
 
|
 
resistant to a chemical
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Mitomycin C
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:27504) Mitomycin C
 
|
 
0.1 ug/ml
 
|-
 
|
 
OMP_AN:27443
 
|
 
 
|
 
OMP:0007247
 
|
 
resistant to a chemical
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:(-)-Epinephrine
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:28918) (-)-Epinephrine
 
|
 
50, 250, 1000 uM
 
|-
 
|
 
OMP_AN:27444
 
|
 
 
|
 
OMP:0007247
 
|
 
resistant to a chemical
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Hydroxyurea
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:44423) Hydroxyurea
 
|
 
1, 5, 10 mM
 
|-
 
|
 
OMP_AN:27445
 
|
 
 
|
 
OMP:0007247
 
|
 
resistant to a chemical
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Phenazine methosulfate (PMS)
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:8055) Phenazine methosulfate (PMS)
 
|
 
0.02, 0.05, 0.1 mM
 
|-
 
|
 
OMP_AN:27446
 
|
 
 
|
 
OMP:0007247
 
|
 
resistant to a chemical
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Chlorpromazine hydrochloride
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:3649) Chlorpromazine hydrochloride
 
|
 
3, 6, 12, 24 uM
 
|-
 
|
 
OMP_AN:27447
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Fusidic acid sodium salt
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:126963539) Fusidic acid sodium salt
 
|
 
1, 5, 20, 50 ug/ml
 
|-
 
|
 
OMP_AN:27448
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Thiolactomycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:445629) Thiolactomycin
 
|
 
1, 5, 50 uM
 
|-
 
|
 
OMP_AN:27449
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Nigericin sodium salt
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:16760591) Nigericin sodium salt
 
|
 
0.1, 1, 5 uM
 
|-
 
|
 
OMP_AN:27450
 
|
 
 
|
 
OMP:0006039
 
|
 
resistant to macrolide
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Azithromycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:2955) Azithromycin
 
|
 
0.02, 0.1, 1 ug/ml
 
|-
 
|
 
OMP_AN:27451
 
|
 
 
|
 
OMP:0006039
 
|
 
resistant to macrolide
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Clarithromycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:3732) Clarithromycin
 
|
 
0.1, 1, 5, 10 ug/ml
 
|-
 
|
 
OMP_AN:27452
 
|
 
 
|
 
OMP:0006039
 
|
 
resistant to macrolide
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Erythromycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:42355) Erythromycin
 
|
 
0.1, 1, 5, 10 ug/ml
 
|-
 
|
 
OMP_AN:27453
 
|
 
 
|
 
OMP:0006039
 
|
 
resistant to macrolide
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Spiramycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:6419898) Spiramycin
 
|
 
1, 5, 20 ug/ml
 
|-
 
|
 
OMP_AN:27454
 
|
 
 
|
 
OMP:0006065
 
|
 
resistant to tetracycline
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Doxycycline hyclate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:34730) Doxycycline hyclate
 
|
 
0.25, 0.5, 0.75, 1 ug/ml
 
|-
 
|
 
OMP_AN:27455
 
|
 
 
|
 
OMP:0006065
 
|
 
resistant to tetracycline
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Minocycline hydrochloride
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:50697) Minocycline hydrochloride
 
|
 
0.2, 0.5, 1 ug/ml
 
|-
 
|
 
OMP_AN:27456
 
|
 
 
|
 
OMP:0006065
 
|
 
resistant to tetracycline
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Tetracycline hydrochloride
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:35006) Tetracycline hydrochloride
 
|
 
0.25, 0.5, 0.75, 1 ug/ml
 
|-
 
|
 
OMP_AN:27457
 
|
 
 
|
 
OMP:0006060
 
|
 
resistant to aminoglycoside
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Amikacin sulfate salt (disulfate)
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:2638) Amikacin sulfate salt (disulfate)
 
|
 
0.05, 0.1, 0.2 ug/ml
 
|-
 
|
 
OMP_AN:27458
 
|
 
 
|
 
OMP:0006060
 
|
 
resistant to aminoglycoside
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Gentamicin sulfate salt
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:5312) Gentamicin sulfate salt
 
|
 
0.05, 0.1 ug/ml
 
|-
 
|
 
OMP_AN:27459
 
|
 
 
|
 
OMP:0006060
 
|
 
resistant to aminoglycoside
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Spectinomycin dihydrochloride pentahydrate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:9217) Spectinomycin dihydrochloride pentahydrate
 
|
 
4, 6 ug/ml
 
|-
 
|
 
OMP_AN:27460
 
|
 
 
|
 
OMP:0006060
 
|
 
resistant to aminoglycoside
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Streptomycin sulfate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:32158) Streptomycin sulfate
 
|
 
0.05 ug/ml
 
|-
 
|
 
OMP_AN:27461
 
|
 
 
|
 
OMP:0006060
 
|
 
resistant to aminoglycoside
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Tobramycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:28864) Tobramycin
 
|
 
0.05, 0.1, 0.2, 0.4 ug/ml
 
|-
 
|
 
OMP_AN:27462
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Amoxicillin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:2676) Amoxicillin
 
|
 
0.25, 0.5, 1, 1.5 ug/ml
 
|-
 
|
 
OMP_AN:27463
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Ampicillin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:28971) Ampicillin
 
|
 
1, 2, 4, 8 ug/ml
 
|-
 
|
 
OMP_AN:27464
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Aztreonam
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:161680) Aztreonam
 
|
 
0.02, 0.04 ug/ml
 
|-
 
|
 
OMP_AN:27465
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Carbenicillin disodium
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:34609) Carbenicillin disodium
 
|
 
0.5, 1, 1.5 ug/ml
 
|-
 
|
 
OMP_AN:27466
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Cefoxitin sodium hydrate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:3501) Cefoxitin sodium hydrate
 
|
 
0.25, 0.5, 0.75, 1 ug/ml
 
|-
 
|
 
OMP_AN:27467
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Cefsulodin sodium salt hydrate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:31380) Cefsulodin sodium salt hydrate
 
|
 
6, 12, 18, 24 ug/ml
 
|-
 
|
 
OMP_AN:27468
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Ceftazidime hydrate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:3509) Ceftazidime hydrate
 
|
 
0.025, 0.05, 0.075 ug/ml
 
|-
 
|
 
OMP_AN:27469
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Mecillinam
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:51208) Mecillinam
 
|
 
0.03, 0.06, 0.09, 0.12 ug/ml
 
|-
 
|
 
OMP_AN:27470
 
|
 
 
|
 
OMP:0006047
 
|
 
resistant to beta-lactam
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Oxacillin sodium salt
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:52134) Oxacillin sodium salt
 
|
 
0.5, 5, 40 ug/ml
 
|-
 
|
 
OMP_AN:27471
 
|
 
 
|
 
OMP:0006043
 
|
 
resistant to quinolone
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Ciprofloxacin hydrochloride hydrate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:59936) Ciprofloxacin hydrochloride hydrate
 
|
 
0.004, 0.006, 0.008 ug/ml
 
|-
 
|
 
OMP_AN:27472
 
|
 
 
|
 
OMP:0006043
 
|
 
resistant to quinolone
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Levofloxacin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:63598) Levofloxacin
 
|
 
0.002 ug/ml
 
|-
 
|
 
OMP_AN:27473
 
|
 
 
|
 
OMP:0006043
 
|
 
resistant to quinolone
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Nalidixic acid sodium salt
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:3864541) Nalidixic acid sodium salt
 
|
 
0.5, 1, 1.5, 2 ug/ml
 
|-
 
|
 
OMP_AN:27474
 
|
 
 
|
 
OMP:0006043
 
|
 
resistant to quinolone
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Norfloxacin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:100246) Norfloxacin
 
|
 
0.01, 0.02, 0.04 ug/ml
 
|-
 
|
 
OMP_AN:27475
 
|
 
 
|
 
OMP:0006043
 
|
 
resistant to quinolone
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Streptonigrin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:9287) Streptonigrin
 
|
 
0.1, 0.2, 0.5 ug/ml
 
|-
 
|
 
OMP_AN:27476
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Chloramphenicol
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:17698) Chloramphenicol
 
|
 
0.5, 1, 1.5, 2 ug/ml
 
|-
 
|
 
OMP_AN:27477
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Isoniazid
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:6030) Isoniazid
 
|
 
0.2, 1, 1.5 mM
 
|-
 
|
 
OMP_AN:27478
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Pyocyanin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:8653) Pyocyanin
 
|
 
0.2, 1, 10 ug/ml
 
|-
 
|
 
OMP_AN:27479
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Hydrogen peroxide
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:16240) Hydrogen peroxide
 
|
 
0.1, 0.5, 1, 2 mM
 
|-
 
|
 
OMP_AN:27480
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Cerulenin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:171741) Cerulenin
 
|
 
1, 2, 4, 6 ug/ml
 
|-
 
|
 
OMP_AN:27481
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:CHIR-090
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:134107 CID:11546620) CHIR-090
 
|
 
0.02, 0.025, 0.04, 0.05, 0.075 ug/ml
 
|-
 
|
 
OMP_AN:27482
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Ethidium Bromide
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:4883) Ethidium Bromide
 
|
 
2, 10, 50 ug/ml
 
|-
 
|
 
OMP_AN:27483
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Rifampicin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:28077) Rifampicin
 
|
 
1, 2 ug/ml
 
|-
 
|
 
OMP_AN:27484
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Azidothymidine
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:10110) Azidothymidine
 
|
 
0.5, 1, 2.5 ng/ml
 
|-
 
|
 
OMP_AN:27485
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Puromycin dihydrochloride
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:8642) Puromycin dihydrochloride
 
|
 
1, 5, 25 ug/ml
 
|-
 
|
 
OMP_AN:27486
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Tunicamycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:29699) Tunicamycin
 
|
 
1, 3, 7.5 ug/ml
 
|-
 
|
 
OMP_AN:27487
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Fosfomycin disodium salt
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:6093162) Fosfomycin disodium salt
 
|
 
1 ug/ml
 
|-
 
|
 
OMP_AN:27488
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Bicyclomycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:60584) Bicyclomycin
 
|
 
1, 10 ug/ml
 
|-
 
|
 
OMP_AN:27489
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:A22
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:2830968) A22
 
|
 
0.5, 2, 5, 15 ug/ml
 
|-
 
|
 
OMP_AN:27490
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:D-Cycloserine
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:40009) D-Cycloserine
 
|
 
16 ug/ml
 
|-
 
|
 
OMP_AN:27491
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Actinomycin D
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:27666 CID:457193) Actinomycin D
 
|
 
2.5, 5, 10, 15 ug/ml
 
|-
 
|
 
OMP_AN:27492
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Bacitracin Zinc Sulfate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:16219032) Bacitracin Zinc Sulfate
 
|
 
100, 200, 300 ug/ml
 
|-
 
|
 
OMP_AN:27493
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Bleomycin sulfate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:34582) Bleomycin sulfate
 
|
 
0.1, 0.5, 1, 2 ug/ml
 
|-
 
|
 
OMP_AN:27494
 
|
 
 
|
 
OMP:0007171
 
|
 
resistant to antimicrobial peptide
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Cecropin B
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CID:16130488) Cecropin B
 
|
 
0.1, 0.3 ug/ml
 
|-
 
|
 
OMP_AN:27495
 
|
 
 
|
 
OMP:0007171
 
|
 
resistant to antimicrobial peptide
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Indolicidin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(UniProtKB:P33046) Indolicidin
 
|
 
0.1 ug/ml
 
|-
 
|
 
OMP_AN:27496
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Phleomycin
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:75044) Phleomycin
 
|
 
0.2, 0.5, 1 ug/ml
 
|-
 
|
 
OMP_AN:27497
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Polymyxin B sulfate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:8310) Polymyxin B sulfate
 
|
 
1, 2, 4, 6 ug/ml
 
|-
 
|
 
OMP_AN:27498
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
temperature:37C
 
*medium:LB agar
 
*medium:Vancomycin HCl hydrate
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some
 
(CHEBI:9932) Vancomycin HCl hydrate
 
|
 
10, 20, 50 ug/ml
 
|-
 
|
 
OMP_AN:27499
 
|
 
 
|
 
OMP:0007876
 
|
 
resistant to an antimicrobial agent
 
|
 
Relative to:
 
 
<hr>Genotype differences:<br>
 
Nothing to compare<br/>
 
<hr>Condition differences:<br>
 
Nothing to compare<br/>
 
|
 
 
*temperature:37C
 
*medium:LB agar
 
*medium:Trimethoprim
 
|
 
ECO:0007005
 
|
 
high throughput direct assay evidence used in manual assertion
 
|
 
PMID:21185072
 
|
 
towards some (CHEBI:45924) Trimethoprim
 
|
 
0.1, 0.2, 0.3, 0.4 ug/ml
 
  
 
|- class="tableEdit_footer"  
 
|- class="tableEdit_footer"  

Revision as of 23:22, 24 September 2019

Strain Summary

Strain Name

Virtual reference strain for Nichols RJ (2011) Cell 144, 143-156.

Synonyms
Taxon Information
  • Pangenome: Escherichia coli
  • Subspecies and/or strain: K-12
  • NCBI Taxonomy ID: 83333
Genotype

DE(araD-araB)567 DE(rhaD-rhaB)568 F- Lambda- hsdR514 lacZ4787(del)::rrnB-3 rph-1

Strain Reference

PMID:21185072[1]

Strain availability
Ancestry
Annotated phenotypes



Notes

OMP_ST:74667 was created to use as the reference (or control) strain for the high-throughput phenotype studies of Nichols RJ et al. (2011) Cell 144:143-156. In this study, fitness in the various growth conditions was determined based on the sizes of spot colonies. Colony sizes were normalized in two steps. First, colony sizes on each individual plate were normalized to correct for systematic differences. Second, the colony sizes for each strain were normalized based on the median colony size of that strain in all 324 conditions.

Of the 4,602 strains that were screened, 4,502 strains were derivatives of E. coli K-12 BW25113; the remaining 100 strains were derivative of E. coli K-12 MG1655. For this reason, we have used the genotype of BW25113 as the genotype for the virtual reference strain.

The collection of mutants that was screened included 4334 deletions of non-essential genes (the Keio Collection ([1]), 148 SPA-tagged derivatives of essential genes ([2] [3]), 9 point-mutant alleles of essential genes (as well as the corresponding control strains that carried the same antibioticR marker linked to the wild-type allele), 2 truncations of essential genes, and 100 deletions of small RNAs and small proteins ([2]). See the original paper for additional details about the strains used in the screen.

Phenotype Annotation

Annotation ID Qualifier OMP ID OMP term name Relative phenotype information Experimental condition ECO ID ECO term name Reference Annotation Extension Notes

OMP_AN:27248

OMP:0007247

resistant to a chemical

Relative to:


Genotype differences:

Nothing to compare


Condition differences:

Nothing to compare

  • temperature:37C
  • medium:LB agar
  • medium:SDS
ECO:0007005

high throughput direct assay evidence used in manual assertion

PMID:21185072[1]

towards some (CHEBI:8984) SDS

concentrations of SDS used were (0.5, 1, 2, 3, or 4%)


Additional Information

Links

References

See Help:References for how to manage references in OMPwiki.

  1. 1.0 1.1 Nichols, RJ et al. (2011) Phenotypic landscape of a bacterial cell. Cell 144 143-56 PubMed OMPwiki page
  2. Hobbs, EC et al. (2010) Small RNAs and small proteins involved in resistance to cell envelope stress and acid shock in Escherichia coli: analysis of a bar-coded mutant collection. J. Bacteriol. 192 59-67 PubMed OMPwiki page