OMP ST:1214 ! Escherichia coli K-12 JW0451

Strain Summary

Strain Name	Escherichia coli K-12 JW0451
Synonyms	BW25113 acrB747(del)::kan, ECK0456
Taxon Information	Pangenome: Escherichia coli Subspecies and/or strain: K-12 NCBI Taxonomy ID: 83333
Genotype	DE(araD-araB)567 DE(rhaD-rhaB)568 F- Lambda- hsdR514 lacZ4787(del)(::rrnB-3) rph-1 acrB747(del)::kan
Strain Reference	other:CGSC PMID:16738554
Strain availability	CGSC
Ancestry	parent:OMP ST:800 ! Escherichia coli K-12 BW25113
Annotated phenotypes
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Phenotype Annotation

Annotation ID	not	OMP ID	OMP term name	Relative phenotype information	Experimental condition	ECO ID	ECO term name	Reference	Annotation Extension	Notes
OMP_AN:1098		increased resistance to organic aromatic compound		Relative to: OMP_AN:817 Genotype differences: +acrB747(del) Condition differences: no differences	medium:procaine (30 ug ml-1)			PMID:21185072	CHEBI:8430 procaine	fitness score = 7.16
OMP_AN:1100		OMP:0007249	Increased sensitivity to a chemical	Relative to: OMP_AN:1099 Genotype differences: +acrB747(del) Condition differences: no differences	medium:EGTA (2.0 ug ml-1)			PMID:21185072	CHEBI:30740 EGTA	fitness score = 3.83
OMP_AN:1102		OMP:0007249	Increased sensitivity to a chemical	Relative to: OMP_AN:1101 Genotype differences: +acrB747(del) Condition differences: no differences	medium:polymixin B (6.0 ug ml-1)			PMID:21185072	CHEBI:8309 polymixin B	fitness score = 4.02
OMP_AN:1104		OMP:0007174	increased resistance to antimicrobial peptide	Relative to: OMP_AN:1103 Genotype differences: +acrB747(del) Condition differences: no differences	medium:vancomycin (10 ug ml-1)			PMID:21185072	CHEBI:28001 vancomycin	fitness score = 3.80
OMP_AN:1105		OMP:0006041	increased resistance to quinolone	Relative to: OMP_AN:703 Genotype differences: +acrB747(del) Condition differences: no differences	medium:doxorubicin (1.0 ug ml-1)			PMID:21185072	CHEBI:28748 doxorubicin	fitness score = 3.70
OMP_AN:1107		OMP:0007249	Increased sensitivity to a chemical	Relative to: OMP_AN:1106 Genotype differences: +acrB747(del) Condition differences: no differences	medium:cholate 0.1%			PMID:21185072	CHEBI:29747 cholate	fitness score = 3.67
OMP_AN:1109		OMP:0006045	increased resistance to beta-lactam compound	Relative to: OMP_AN:1108 Genotype differences: +acrB747(del) Condition differences: no differences	medium:amoxicillin (1.5 ug ml-1)			PMID:21185072	CHEBI:2676 amoxicillin	itness score = 3.56
OMP_AN:1111		OMP:0006045	increased resistance to beta-lactam compound	Relative to: OMP_AN:1110 Genotype differences: +acrB747(del) Condition differences: no differences	medium:ampicillin (2.0 ug ml-1)			PMID:21185072	CHEBI:28971 ampicillin	fitness score = 3.28
OMP_AN:1113		OMP:0006045	increased resistance to beta-lactam compound	Relative to: OMP_AN:1112 Genotype differences: +acrB747(del) Condition differences: no differences	medium:aztreonam (0.002 ug ml-1)			PMID:21185072	CHEBI:161680 aztreonam	fitness score = 3.16
OMP_AN:1115		OMP:0005097	increased resistance to UV radiation	Relative to: OMP_AN:1114 Genotype differences: +acrB747(del) Condition differences: no differences	medium:UV (24 seconds)			PMID:21185072		fitness score = 3.20
OMP_AN:1117		OMP:0007249	Increased sensitivity to a chemical	Relative to: OMP_AN:1116 Genotype differences: +acrB747(del) Condition differences: no differences	medium:ethanol (6.0 ug ml-1)			PMID:21185072	CHEBI:16236 ethanol	fitness score = 3.05
OMP_AN:1130		OMP:0006040	decreased resistance to quinolone	Relative to: OMP_AN:841 Genotype differences: +acrB747(del) Condition differences: no differences	medium:dibucaine (1.2 ug ml-1)			PMID:21185072	CHEBI:247956 dibucaine	fitness score = -26.92
OMP_AN:1162		OMP:0007250	decreased sensitivity to a chemical	Relative to: OMP_AN:689 Genotype differences: +acrB747(del) Condition differences: no differences	medium:propidium iodide (50 ug ml-1)			PMID:21185072	CHEBI:51240 propidium iodide	fitness score = -23.56
OMP_AN:1163		OMP:0005276	decreased resistance to organic heterocyclic compound	Relative to: OMP_AN:822 Genotype differences: +acrB747(del) Condition differences: no differences	medium:novobiocin (30 ug ml-1)			PMID:21185072	CHEBI:28368 novobiocin	fitness score = -26.29
OMP_AN:1164		OMP:0006044	decreased resistance to beta-lactam	Relative to: OMP_AN:849 Genotype differences: +acrB747(del) Condition differences: no differences	medium:oxacillin (40 ug ml-1)			PMID:21185072	CHEBI:7809 oxacillin	fitness score = -25.93
OMP_AN:1165		OMP:0007250	decreased sensitivity to a chemical	Relative to: OMP_AN:855 Genotype differences: +acrB747(del) Condition differences: no differences	medium:mitomycinc (0.1 ug ml-1)			PMID:21185072	CHEBI:27504 mitomycinc	fitness score = -24.34
OMP_AN:1166		OMP:0005276	decreased resistance to organic heterocyclic compound	Relative to: OMP_AN:835 Genotype differences: +acrB747(del) Condition differences: no differences	medium:ethidium bromide (50 ug ml-1)			PMID:21185072	CHEBI:4883 ethidium bromide	fitness score = -22.13
OMP_AN:1167		OMP:0006067	decreased resistance to chloramphenicol	Relative to: OMP_AN:649 Genotype differences: +acrB747(del) Condition differences: no differences	medium:chloramphenicol (2.0 ug ml-1)			PMID:21185072	CHEBI:17698 chloramphenicol	fitness score = -16.67
OMP_AN:1168		OMP:0007385	decreased resistance benzamides	Relative to: OMP_AN:659 Genotype differences: +acrB747(del) Condition differences: no differences	medium:CHIR-090 (0.075 ug ml-1)			PMID:21185072	PubChem CID:11546620 Chir-090	fitness score = -10.62
OMP_AN:1169		OMP:0006036	decreased resistance to macrolide	Relative to: OMP_AN:872 Genotype differences: +acrB747(del) Condition differences: no differences	medium:erythromycin (10.0 ug ml-1)			PMID:21185072	CHEBI:48923 erythromycin	fitness score = -20.89
OMP_AN:1170		OMP:0007250	decreased sensitivity to a chemical	Relative to: OMP_AN:845 Genotype differences: +acrB747(del) Condition differences: no differences	medium:deoxycholate 2.0%			PMID:21185072	CHEBI:23614 deoxycholate	fitness score = -20.88
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References

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