Difference between revisions of "Lactose metabolism"

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*Comparison of beta-galactosidases from normal (i-o+z+) and operator constitutive (i-ocz+) strains of E. coli<ref name='PMID:5327255'/>
 
*Comparison of beta-galactosidases from normal (i-o+z+) and operator constitutive (i-ocz+) strains of E. coli<ref name='PMID:5327255'/>
 
*Allelic amber and ochre suppressors<ref name='PMID:5760539'/>
 
*Allelic amber and ochre suppressors<ref name='PMID:5760539'/>
−
**RESTORATION OF OPERON ACTIVITY BY SUPPRESSORS<ref name='PMID:14068553'/>
+
*RESTORATION OF OPERON ACTIVITY BY SUPPRESSORS<ref name='PMID:14068553'/>
 
*Genetic mapping of the regulator and operator genes of the lac operon<ref name='PMID:4939632'/>
 
*Genetic mapping of the regulator and operator genes of the lac operon<ref name='PMID:4939632'/>
 +
*Genetic evidence that the operator locus is distinct from the the z gene in the lac operon of Escherichia coli<ref name='PMID:4897792'/>
  
 
==Papers about the Polarity of the ''lac'' Operon==
 
==Papers about the Polarity of the ''lac'' Operon==

Revision as of 17:12, 15 November 2010

General

  • Pure Clones of Lactose-negative mutants obtained in Escherichia coli after treatment with 5-bromouracil[1]
  • Recombination analysis of bacterial heredity[2]
  • Allelic Relationships and Reverse Mutation in Escherichia Coli[3]
  • Transposition of the lac region of Escherichia coli. I. Inversion of the lac operon and transduction of lac by phi80[4]
  • Transposition of the Lac region of E. coli[5]
  • Mutational alteration of the maximal level of Lac operon expression[6]
  • Frameshift mutations in the lactose operon of E. coli[7]
  • Mutagens which cause deletions in Escherichia coli[8]

Papers about the Promoter, Operator, and General Regulation of Lactose Metabolism

  • Genetic regulatory mechanisms in the synthesis of proteins[9]
  • A DELETION ANALYSIS OF THE LAC OPERATOR REGION IN ESCHERICHIA COLI[10]
  • Comparison of beta-galactosidases from normal (i-o+z+) and operator constitutive (i-ocz+) strains of E. coli[11]
  • Allelic amber and ochre suppressors[12]
  • RESTORATION OF OPERON ACTIVITY BY SUPPRESSORS[13]
  • Genetic mapping of the regulator and operator genes of the lac operon[14]
  • Genetic evidence that the operator locus is distinct from the the z gene in the lac operon of Escherichia coli[15]

Papers about the Polarity of the lac Operon

  • A polycistronic messenger RNA associated with beta-galactosidase induction[16]
  • Nonsense mutants and polarity in the lac operon of Escherichia coli[17]
  • Transduction by bacteriophage P-1 and the properties of the lac genetic region in E. coli and S. dysenteriae[18]
  • The influence of deletions on polarity[19]

Papers about Proteins Involved in Lactose Metabolism

  • lacI
    • On the nature of the repressor of beta-galactosidase synthesis in Escherichia coli[20]
    • NON-INDUCIBLE MUTANTS OF THE REGULATOR GENE IN THE "LACTOSE" SYSTEM OF ESCHERICHIA COLI[21]
    • The genetic control and cytoplasmic expression of “Inducibility” in the synthesis of β-galactosidase by E. coli[22]
    • NON-INDUCIBLE MUTANTS OF THE REGULATOR GENE IN THE "LACTOSE" SYSTEM OF ESCHERICHIA COLI[21]
    • Suppressible regulator constitutive mutants of the lactose system in Escherichia coli[23]
    • Isolation of the lac repressor[24]
    • Mutants that make more lac repressor[25]
  • lacZ
    • The beta-galactosidase of lactose mutants of Escherichia coli, K-12[26]
    • MULTIPLE MOLECULAR FORMS OF BETA-GALACTOSIDASE[27]
    • THE ORDER OF INDUCTION AND DEINDUCTION OF THE ENZYMES OF THE LACTOSE OPERON IN E. COLI[28]
    • EVIDENCE FOR NONIDENTICAL CHAINS IN THE BETA-GALACTOSIDASE OF ESCHERICHIA COLI K12[29]
    • Inhibition of the synthesis of beta-galactosidase in Escherichia coli by 2-nitrophenyl-beta-D-fucoside[30]
  • lacY
    • Isolation, genetic analysis, and characterization of Escherichia coli mutants with defects in the lacY gene[31]
    • Interaction of sugars with the membrane protein component of the lactose transport system of Escherichia coli[32]
    • Defective lactose utilization by a mutant of Escherichia coli energy-uncoupled for lactose transport. The advantages of active transport versus facilitated diffusion.[33]
    • A mutant in Escherichia coli energy-uncoupled for lactose transport defect in the lactose-operon[34]
    • Specific labeling and partial purification of the M protein, a component of the beta-galactoside transport system of Escherichia coli[35]
    • The nature of mutants in the lac promoter region[36]
  • lacA
    • Thiogalactoside transacetylase[37]
    • Transposition of the lac region of Escherichia coli. II. On the role of thiogalactoside transacetylase in lactose metabolism[38]
    • Transposition of the lac region of Escherichia coli. II. On the role of thiogalactoside transacetylase in lactose metabolism[38]
  • Procedures
    • A SPECTROPHOTOMETRIC ASSAY FOR THIOGALACTOSIDE TRANSACETYLASE[39]
    • PURIFICATION, COMPOSITION, AND MOLECULAR WEIGHT OF THE BETA-GALACTOSIDASE OF ESCHERICHIA COLI K12[40]

References

  1. ↑ WITKIN, EM & SICURELLA, NA (1964) PURE CLONES OF LACTOSE-NEGATIVE MUTANTS OBTAINED IN ESCHERICHIA COLI AFTER TREATMENT WITH 5-BROMOURACIL. J. Mol. Biol. 8 610-3 PubMed OMPwiki page
  2. ↑ LEDERBERG, J et al. (1951) Recombination analysis of bacterial heredity. Cold Spring Harb. Symp. Quant. Biol. 16 413-43 PubMed OMPwiki page
  3. ↑ Lederberg, EM (1952) Allelic Relationships and Reverse Mutation in Escherichia Coli. Genetics 37 469-83 PubMed OMPwiki page
  4. ↑ Beckwith, JR & Signer, ER (1966) Transposition of the lac region of Escherichia coli. I. Inversion of the lac operon and transduction of lac by phi80. J. Mol. Biol. 19 254-65 PubMed OMPwiki page
  5. ↑ Beckwith, JR et al. (1966) Transposition of the Lac region of E. coli. Cold Spring Harb. Symp. Quant. Biol. 31 393-401 PubMed OMPwiki page
  6. ↑ Scaife, J & Beckwith, JR (1966) Mutational alteration of the maximal level of Lac operon expression. Cold Spring Harb. Symp. Quant. Biol. 31 403-8 PubMed OMPwiki page
  7. ↑ Malamy, MH (1966) Frameshift mutations in the lactose operon of E. coli. Cold Spring Harb. Symp. Quant. Biol. 31 189-201 PubMed OMPwiki page
  8. ↑ Schwartz, DO & Beckwith, JR (1969) Mutagens which cause deletions in Escherichia coli. Genetics 61 371-6 PubMed OMPwiki page
  9. ↑ JACOB, F & MONOD, J (1961) Genetic regulatory mechanisms in the synthesis of proteins. J. Mol. Biol. 3 318-56 PubMed OMPwiki page
  10. ↑ BECKWITH, JR (1964) A DELETION ANALYSIS OF THE LAC OPERATOR REGION IN ESCHERICHIA COLI. J. Mol. Biol. 8 427-30 PubMed OMPwiki page
  11. ↑ Steers, E Jr et al. (1965) Comparison of beta-galactosidases from normal (i-o+z+) and operator constitutive (i-ocz+) strains of E. coli. Proc. Natl. Acad. Sci. U.S.A. 54 1174-81 PubMed OMPwiki page
  12. ↑ Ohlsson, BM et al. (1968) Allelic amber and ochre suppressors. J. Mol. Biol. 36 209-18 PubMed OMPwiki page
  13. ↑ BECKWITH, J (1963) RESTORATION OF OPERON ACTIVITY BY SUPPRESSORS. Biochim. Biophys. Acta 76 162-4 PubMed OMPwiki page
  14. ↑ Davies, J & Jacob, F (1968) Genetic mapping of the regulator and operator genes of the lac operon. J. Mol. Biol. 36 413-7 PubMed OMPwiki page
  15. ↑ Reznikoff, WS & Beckwith, JR (1969) Genetic evidence that the operator locus is distinct from the the z gene in the lac operon of Escherichia coli. J. Mol. Biol. 43 215-8 PubMed OMPwiki page
  16. ↑ Kiho, Y & Rich, A (1965) A polycistronic messenger RNA associated with beta-galactosidase induction. Proc. Natl. Acad. Sci. U.S.A. 54 1751-8 PubMed OMPwiki page
  17. ↑ Newton, WA et al. (1965) Nonsense mutants and polarity in the lac operon of Escherichia coli. J. Mol. Biol. 14 290-6 PubMed OMPwiki page
  18. ↑ FRANKLIN, NC & LURIA, SE (1961) Transduction by bacteriophage P-1 and the properties of the lac genetic region in E. coli and S. dysenteriae. Virology 15 299-311 PubMed OMPwiki page
  19. ↑ Zipser, D & Newton, A (1967) The influence of deletions on polarity. J. Mol. Biol. 25 567-9 PubMed OMPwiki page
  20. ↑ PARDEE, AB & PRESTIDGE, LS (1959) On the nature of the repressor of beta-galactosidase synthesis in Escherichia coli. Biochim. Biophys. Acta 36 545-7 PubMed OMPwiki page
  21. ↑ 21.0 21.1 WILLSON, C et al. (1964) NON-INDUCIBLE MUTANTS OF THE REGULATOR GENE IN THE "LACTOSE" SYSTEM OF ESCHERICHIA COLI. J. Mol. Biol. 8 582-92 PubMed OMPwiki page
  22. ↑ () PubMed OMPwiki page
  23. ↑ Müller-Hill, B (1966) Suppressible regulator constitutive mutants of the lactose system in Escherichia coli. J. Mol. Biol. 15 374-6 PubMed OMPwiki page
  24. ↑ Gilbert, W & Müller-Hill, B (1966) Isolation of the lac repressor. Proc. Natl. Acad. Sci. U.S.A. 56 1891-8 PubMed OMPwiki page
  25. ↑ Müller-Hill, B et al. (1968) Mutants that make more lac repressor. Proc. Natl. Acad. Sci. U.S.A. 59 1259-64 PubMed OMPwiki page
  26. ↑ LESTER, G (1952) The beta-galactosidase of lactose mutants of Escherichia coli, K-12. Arch. Biochem. Biophys. 40 390-401 PubMed OMPwiki page
  27. ↑ APPEL, SH et al. (1965) MULTIPLE MOLECULAR FORMS OF BETA-GALACTOSIDASE. J. Mol. Biol. 11 12-22 PubMed OMPwiki page
  28. ↑ ALPERS, DH & TOMKINS, GM (1965) THE ORDER OF INDUCTION AND DEINDUCTION OF THE ENZYMES OF THE LACTOSE OPERON IN E. COLI. Proc. Natl. Acad. Sci. U.S.A. 53 797-802 PubMed OMPwiki page
  29. ↑ STEERS, E Jr et al. (1965) EVIDENCE FOR NONIDENTICAL CHAINS IN THE BETA-GALACTOSIDASE OF ESCHERICHIA COLI K12. J. Biol. Chem. 240 2478-84 PubMed OMPwiki page
  30. ↑ Jayaraman, K et al. (1966) Inhibition of the synthesis of beta-galactosidase in Escherichia coli by 2-nitrophenyl-beta-D-fucoside. J. Mol. Biol. 18 339-43 PubMed OMPwiki page
  31. ↑ Hobson, AC et al. (1977) Isolation, genetic analysis, and characterization of Escherichia coli mutants with defects in the lacY gene. J. Bacteriol. 131 830-8 PubMed OMPwiki page
  32. ↑ Carter, JR et al. (1968) Interaction of sugars with the membrane protein component of the lactose transport system of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 60 725-32 PubMed OMPwiki page
  33. ↑ Kusch, M & Wilson, TH (1973) Defective lactose utilization by a mutant of Escherichia coli energy-uncoupled for lactose transport. The advantages of active transport versus facilitated diffusion. Biochim. Biophys. Acta 311 109-22 PubMed OMPwiki page
  34. ↑ Wilson, TH et al. (1970) A mutant in Escherichia coli energy-uncoupled for lactose transporta defect in the lactose-operon. Biochem. Biophys. Res. Commun. 40 1409-14 PubMed OMPwiki page
  35. ↑ Fox, CF & Kennedy, EP (1965) Specific labeling and partial purification of the M protein, a component of the beta-galactoside transport system of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 54 891-9 PubMed OMPwiki page
  36. ↑ Arditti, RR et al. (1968) The nature of mutants in the lac promoter region. J. Mol. Biol. 38 421-6 PubMed OMPwiki page
  37. ↑ ZABIN, I et al. (1962) Thiogalactoside transacetylase. J. Biol. Chem. 237 253-7 PubMed OMPwiki page
  38. ↑ 38.0 38.1 Fox, CF et al. (1966) Transposition of the lac region of Escherichia coli. II. On the role of thiogalactoside transacetylase in lactose metabolism. J. Mol. Biol. 19 576-9 PubMed OMPwiki page
  39. ↑ ALPERS, DH et al. (1965) A SPECTROPHOTOMETRIC ASSAY FOR THIOGALACTOSIDE TRANSACETYLASE. J. Biol. Chem. 240 10-3 PubMed OMPwiki page
  40. ↑ CRAVEN, GR et al. (1965) PURIFICATION, COMPOSITION, AND MOLECULAR WEIGHT OF THE BETA-GALACTOSIDASE OF ESCHERICHIA COLI K12. J. Biol. Chem. 240 2468-77 PubMed OMPwiki page