Difference between revisions of "Main Page"
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<center>Questions? Contact us at {{Email}}.</center> | <center>Questions? Contact us at {{Email}}.</center> | ||
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<!---------"WELCOME TO THE MICROBIAL PHENOTYPES WIKI" -----------> | <!---------"WELCOME TO THE MICROBIAL PHENOTYPES WIKI" -----------> | ||
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<div style="font-size:172%; border:none; margin:0; padding:.1em; color:#000;">Welcome to the [[OMPWiki:About|Microbial Phenotypes Wiki]],</div> | <div style="font-size:172%; border:none; margin:0; padding:.1em; color:#000;">Welcome to the [[OMPWiki:About|Microbial Phenotypes Wiki]],</div> | ||
− | + | Web-based community resource designed to display microbial phenotypes and the methods used to study them. | |
− | Web-based community resource designed to display microbial phenotypes | + | <!-- portals --> |
− | and the methods used to study them.< | + | |-style="vertical-align:top;" |
− | </ | + | <!----------PORTAL LIST ON LEFT-HAND SIDE--------> |
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+ | <!----------PORTAL LIST in middle--------> | ||
+ | | | ||
+ | == Phenotypes (OMP) == | ||
+ | * [[:Category:OMP:0000000_!_microbial_phenotype|Browse OMP]] | ||
+ | * [https://github.com/microbialphenotypes/OMP-ontology Latest ontology versions] | ||
+ | * [https://github.com/microbialphenotypes/OMP-ontology/issues Term issue tracker] | ||
<!----------PORTAL LIST ON RIGHT-HAND SIDE--------> | <!----------PORTAL LIST ON RIGHT-HAND SIDE--------> | ||
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− | * [[: | + | == Evidence & Conclusion Ontology == |
− | * [[ | + | * [[:Category:ECO:0000000_!_evidence|Browse ECO]] |
− | * [[ | + | * [https://github.com/evidenceontology/evidenceontology/issues ECO issue tracker] |
− | * [[: | + | * [https://github.com/evidenceontology/evidenceontology ECO main repository] |
+ | * [http://evidenceontology.org Official ECO website] | ||
+ | * [http://bioportal.bioontology.org/ontologies/1012 ECO on BioPortal] | ||
+ | | | ||
+ | == Misc. == | ||
+ | [[OmpWiki:Membership|Membership]] | ||
+ | ;Phenotype Data browsers | ||
+ | *[[Special:RNAPchemicalgenetics|Shiver et al. (2020) Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs. BioRxiv]] | ||
+ | *[[Special:ECGASpecialpage|Xia J et al. (2019) Bacteria-to-human protein networks reveal origins of endogenous DNA damage. Cell. 176:127-143.e24.]] | ||
+ | *[[Special:CamposSpecialpage|Campos et al. (2018) Genomewide phenotypic analysis of growth, cell morphogenesis, and cell cycle events in ''Escherichia coli''. Mol Syst Biol. 14(6):e7573.]] | ||
+ | *[[Special:Ecolispecialpage_price|Price et al. (2018) Mutant phenotypes for thousands of bacterial genes of unknown function. Nature. 557(7706):503-509.]] | ||
+ | *[[Special:Specialpeterspage|Peters JM et al. (2016) A comprehensive, CRISPR-based functional analysis of essential genes in bacteria. Cell. 165:1493-1506.]] | ||
+ | *[[Special:Ecolispecialpage|Nichols et al. (2010) Phenotypic landscape of a bacterial cell. Cell. 144:143-56.]] Fitness of 3,979 ''E. coli'' mutants in 324 growth conditions. | ||
+ | |||
+ | [https://github.com/microbialphenotypes/OMPwiki/issues Bug tracker for OMPwiki] | ||
+ | |||
|} | |} | ||
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===News=== | ===News=== | ||
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+ | =====OMP February 2024 Release===== | ||
+ | We are pleased to announce the February 2024 release of the Ontology of Microbial Phenotypes (OMP) is available at: | ||
+ | https://github.com/microbialphenotypes/OMP-ontology/tree/master | ||
=== Search Pages of Interest === | === Search Pages of Interest === | ||
*[[OMP_summary|Summary table]] of all entries in the phenotype tables. | *[[OMP_summary|Summary table]] of all entries in the phenotype tables. | ||
*We are starting to collect [[Categories to Search|information on methods]]. You can contribute to OMP by adding methods and/or references. | *We are starting to collect [[Categories to Search|information on methods]]. You can contribute to OMP by adding methods and/or references. |
Latest revision as of 18:37, 21 March 2024
What are microbial phenotypes & why do they need an ontology?A phenotype is the expression of a genotype (i.e. the full genetic complement of an organism) in a given environment. For example, eye color, number of seeds per pod, and coat color are phenotypic traits that can be observed in flies, lupines, and ponies, respectively. Within an individual organism, both changes in genetic makeup, such as from bacterial conjugation, and variation in gene expression can result in different phenotypes under similar environmental conditions. Conversely, environmental variation can lead to different outcomes for genetically identical organisms, through variable gene expression. Myriad genetically and taxonomically diverse microbes exhibit countless variability in their morphological and physiological traits, both within and among species. Oftentimes these result in unique and exquisite manifestations, such as the symbiosis between the bioluminescent Vibrio fischeri bacterium and its squid host Euprymna scolopes. Characterization of phenotypes is critically important for medical microbial identification, and many unique biotechnological applications of microbes are rooted in phenotypes. Genetic manipulation with associated phenotypic characterization remains an important tool for determining protein function in microorganisms amenable to manipulation, such as Escherichia coli. To facilitate research in all of these areas, we are developing the Ontology of Microbial Phenotypes to allow for standardized capture of essential phenotypic information.
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NewsOMP February 2024 ReleaseWe are pleased to announce the February 2024 release of the Ontology of Microbial Phenotypes (OMP) is available at: https://github.com/microbialphenotypes/OMP-ontology/tree/master Search Pages of Interest
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