https://microbialphenotypes.org/wiki/index.php?action=history&feed=atom&title=Category%3AECO%3A0001810_%21_DNAse_footprinting_evidence 2026-06-08T10:50:44Z Revision history for this page on the wiki MediaWiki 1.31.1 https://microbialphenotypes.org/wiki/index.php?title=Category:ECO:0001810_!_DNAse_footprinting_evidence&diff=18367&oldid=prev 2015-12-18T08:01:10Z

<p>Add page for ECO:0001810_!_DNAse_footprinting_evidence</p> <p><b>New page</b></p><div>{{Autobox|1='''id:''' ECO:0001810&lt;br&gt;<br /> '''name:''' DNAse footprinting evidence&lt;br&gt;<br /> '''def:''' &quot;A type of nucleic acid binding evidence where proteins that have been bound to DNA protect a binding site from enzymatic cleavage with DNAse, thereby detecting protein-DNA interactions.&quot; [ECO:SW, PMID:212715, PMID:22194258]&lt;br&gt;<br /> '''synonym:''' &quot;DNase protection&quot; RELATED []&lt;br&gt;<br /> '''is_a:''' [[:Category:ECO:0000136 ! nucleic acid binding evidence|ECO:0000136 ! nucleic acid binding evidence]][[Category:ECO:0000136 ! nucleic acid binding evidence|ECO:0000136 ! nucleic acid binding evidence]]&lt;br&gt;<br /> '''comment:''' In DNAse footingprinting amplified DNA combined with TF and DNAse is electrophoresed for fragment comparison with a non-TF control sample. TF-bound fragments do not appear in the gel. Such fragments can be isolated, purified, and sequenced. This technique is often used to identify the binding motif of a TF resolving the protected region to 50-100 bp which can be further examined for TF-binding sites.&lt;br&gt;<br /> }}<br /> == Usage Notes ==<br /> <br /> <br /> ==References ==<br /> {{RefHelp}}<br /> &lt;references/&gt;</div>

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