PMID:827549

From OMPwiki
Jump to: navigation, search
Citation

Munch-Petersen, A and Mygind, B (1976) Nucleoside transport systems in Escherichia coli K12: specificity and regulation.J. Cell. Physiol. 89:551-9

Abstract

Two nucleoside transport systems have been verified and separated by mating and recombination experiments. The recipient strain was a mutant which is negative for transport of all nucleosides. The two systems differ in specificity and in regulation. One system transports pyrimidine and adenine nucleosides. It is regulated by the cytR gene. The other system transports all nucleosides and is regulated by the cytR as well as by the deoR genes. Enzyme assays performed on whole cells of strains, able or unable to transport nucleosides, indicate that the nucleoside catabolizing enzymes are located inside the permeability barrier of the cell.

Links

PubMed Online version:10.1002/jcp.1040890410

Keywords

Biological Transport, Active; Cytidine; Cytidine Deaminase; Escherichia coli; Genes, Regulator; Guanosine; Mutation; Nucleosides; Purine-Nucleoside Phosphorylase; Recombination, Genetic; Thymidine; Thymidine Phosphorylase; Uridine Phosphorylase

Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain:
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: nupC nupG
  • Genotype of Experimental Strain : nupC - nupG -
  • Reference Condition:
OMP:0000276

increased resistance to antimicrobial compound

ECO:0000094

biological assay data

  • Fluorouracil resistance

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: SO736
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: gru
  • Genotype of Experimental Strain : gru +
  • Reference Condition:
OMP:0000276

increased resistance to antimicrobial compound

ECO:0000094

biological assay data

resistant to showdomycin

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain:
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: cru
  • Genotype of Experimental Strain : cru +
  • Reference Condition:

OOMP:0000276

increased resistance to antimicrobial compound

ECO:0000094

biological assay data

Showdomycin sensitivty

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain:
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: nupC nupG
  • Genotype of Experimental Strain : nupC - nupG -
  • Reference Condition:
OMP:0000276

increased resistance to antimicrobial compound

ECO:0000094

biological assay data

  • Fluoruridine resistance

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain:
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: nupC nupG
  • Genotype of Experimental Strain : nupC - nupG -
  • Reference Condition:
OMP:0000276

increased resistance to antimicrobial compound

ECO:0000094

biological assay data

  • Fluorodeoxycytidine resistance


Notes

References

See Help:References for how to manage references in OMPwiki.