PMID:4916925

From OMPwiki
Jump to: navigation, search
Citation

Hazelbauer, GL, Mesibov, RE and Adler, J (1969) Escherichia coli mutants defective in chemotaxis toward specific chemicals. Proc. Natl. Acad. Sci. U.S.A. 64:1300-7

Abstract

Mutants of Escherichia coli K12 have been found which fail to carry out chemotaxis toward certain chemicals only. One mutant exhibits greatly reduced chemotaxis toward L-serine but has no detectable defect either in uptake or in oxidative metabolism of that compound. Another mutant is not attracted to D-galactose and certain related sugars. There is a correlation between the galactose chemotaxis defect and a defect in galactose uptake, perhaps indicating a common component for chemotaxis and uptake systems. The results are discussed in terms of a model for chemotaxis in which attractants are detected by specific "chemoreceptors."

Links

PubMed PMC223283

Keywords

Chemotaxis; Escherichia coli; Galactose/metabolism; Genetics, Microbial; Glucose/metabolism; Models, Biological; Mutation; Oxygen Consumption; Receptors, Drug; Ribose/metabolism; Serine/metabolism

Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: Escherichia coli K-12
  • Substrain: AW518
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: tsr+
  • Genotype of Experimental Strain : tsr-1
  • Reference Condition: semisolid tryptone agar, 35C
  • Experimental Condition: semisolid tryptone agar, 35C
OMP:0007041

decreased positive chemotaxis

ECO:0000182

in vitro culture assay evidence


Notes

References

See Help:References for how to manage references in OMPwiki.