Hazelbauer, GL, Mesibov, RE and Adler, J (1969) Escherichia coli mutants defective in chemotaxis toward specific chemicals. Proc. Natl. Acad. Sci. U.S.A. 64:1300-7
Mutants of Escherichia coli K12 have been found which fail to carry out chemotaxis toward certain chemicals only. One mutant exhibits greatly reduced chemotaxis toward L-serine but has no detectable defect either in uptake or in oxidative metabolism of that compound. Another mutant is not attracted to D-galactose and certain related sugars. There is a correlation between the galactose chemotaxis defect and a defect in galactose uptake, perhaps indicating a common component for chemotaxis and uptake systems. The results are discussed in terms of a model for chemotaxis in which attractants are detected by specific "chemoreceptors."
Chemotaxis; Escherichia coli; Galactose/metabolism; Genetics, Microbial; Glucose/metabolism; Models, Biological; Mutation; Oxygen Consumption; Receptors, Drug; Ribose/metabolism; Serine/metabolism
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Materials and Methods Used
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|Phenotype of||Taxon Information||Genotype Information (if known)||Condition Information||OMP ID||OMP Term Name||ECO ID||ECO Term Name||Notes||Status|
a mutation or genetic difference within a strain
decreased positive chemotaxis
in vitro culture assay evidence
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