PMID:4571524

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Citation

Iwakura, Y, Ishihama, A and Yura, T (1973) RNA polymerase mutants of Escherichia coli. Streptolydigin resistance and its relation to rifampicin resistance.Mol. Gen. Genet. 121:181-96

Abstract

No abstract in PubMed

Links

PubMed

Keywords

Anti-Bacterial Agents; DNA-Directed RNA Polymerases; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Mutation; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Pyrans; Pyrroles; RNA; Rifampin

Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

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Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: KY1343
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: rpoB
  • Genotype of Experimental Strain : rpoB
  • Reference Condition:
OMP:0000276

increased resistance to antimicrobial compound

ECO:0000178

in vivo assay data

Resistance to Streptolydigin. in vivo.

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: KY1343
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: rpoB
  • Genotype of Experimental Strain : rpoB
  • Reference Condition:
OMP:0000276

increased resistance to antimicrobial compound

ECO:0000182

in vitro culture assay data

Resistance to Streptolydigin. In vitro.


Notes

ECO terms need to be more specific. Terms have been requested. In vivo solid PG medium. In vitro is a crude extracts. see table 2 comments for more detail.

OMP term: need to make term. Streptolydigin antbiotic resistance. Seems to block transcription but need to verify before submitting a new OMP term request.

References

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